Transcript Slide 1

Recognition Of Team Science
Faculty Appointments, Promotions and Titles at
The Geisel School of Medicine at Dartmouth
“Recognition by peers as an investigator whose work has been instrumental in
promoting significant advances in her/his field of inquiry, inclusive of basic
research, clinical research, pedagogy and health care delivery science.
Hallmarks of recognition include both those made as an individual and those
made as part of a larger, cooperative team.”
Dartmouth Cluster Initiative
(e.g., “Big Data”)
“Solutions, breakthroughs, and advances often arise from collaborative efforts that
transcend the traditional boundaries of academic disciplines. The cluster initiative, through
faculty collaboration and targeted hiring, will provide the critical mass and spectrum of
expertise necessary to shape and advance the understanding of complex problems,
emerging issues, and future societal challenges.
The initiative will establish cohorts of scholars focused on new intellectual themes or
questions that cut across disciplines, departments, and schools.”
Use of Developmental Funds
CCSG Developmental Funds
Budgeted Uses
Pilot Projects
New Faculty
Shared Resources
Technology/Methodology
5y Total
$687,853
$315,000
$60,000
$10,000
Programs
Cancer Control
Cancer Epidemiology
Molecular Therapeutics
Cancer Mechanisms
Cancer Imaging and Radiobiology
Immunology and Cancer
Immunotherapy
Totals
Value of peer –reviewed grants for
these PIs or as a consequence of
pilots
Ratio: Peer-reviewed grants/CCSG
investment
CCSG Supported
Number of
recruitments
supported
1
3
1
1
0
0
Number of
CCSG Pilot
Awards
7
2
11
1
6
4
6
31
$6,565,802
$16,307,274
21:1
23.7:1
Pilot Projects
• NCCC (Prouty): $250,000
• ACS Institutional Grant: $150,000
• Hopeman Cancer Clinical & Population Science: $200,000
• Cancer Nanotechnology: $60,000
• Cancer Comparative Effectiveness
• Cancer Program Projects LOIs
• LOIs for Foundation Cancer Proposals: V Foundation, Komen
Shared Resources add Value to NCCC
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New Shared Resources and Services: Trace Elements, geospatial
Equipment Purchases: 9T MRI, Neogene sequencing platforms
Use of Shared Resources
Programs
CC
CE
CM
MT
CIR
ICI
X
X
X
X
X
X
Trace Elements
X
X
X
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X
Genomics and Mol. Biol.
X
X
X
X
X
Shared Resource
Biostatistics
Bioinformatics
X
X
X
X
X
X
Immune Monitoring and FC
X
X
X
X
X
X
Clinical Pharmacology
X
X
X
Irrad.,PreClin. Imag., Micrscpy.
X
X
X
X
X
X
X
X
X
X
X
X
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Pathology
Transgenics & Gen. Constructs
X
X
Early Phase Study Program Process
2008
2012
Protocol Specific Research Support
2013
2014
Early Phase Clinical Research Support
LoI
Process
for
Early Phase
Clinical
Research
Bench
To/from
Bedside
Formalize
Early Phase Trial
Clinical
Oncology Group
LoI Process
for
Early Phase
Clinical
Research
DH Genetic
Research
Biobank
Molecular
Tumor
Board
NCCC Strategic Plan 2012-2017
41st Year
An NCI-Designated Comprehensive Cancer Center
MISSION, VISION, and VALUES
Research
Care & Treatment
Innovate to control cancer through research
Guide informed decision making by patients and families,
and deliver integrated patient care
Basic Science & Translation
Recognition of the essential value of innovative partnerships between clinical
providers and research scientists to improve cancer treatment
Prevention
Education
Improve population health by reducing environmental
risk, lifestyle intervention and high value screening
Contribute to a sustainable health system by training
scientists and doctors in oncology and patient-centered
care
Population Health & Care
Commitment to advance the field: innovation in clinical practice and the
technology for high value research
People & Resources
Accountability for best uses of institutional resources in research, treatment,
prevention, and education
PERFORMANCE INDICATORS
Clinical Trials
Patients Accrued to Trials 2012 - 6% 2014 % 2017 ___%
Trials Closed w/ Attained Target Accrual 2012 ___% 2014 ___% 2017 ___%
Number of D-studies opened annually 2012 - 20 2014 ____ 2017 ____
Completed Quality Improvement Projects
Pathway Compliance
Tumor Board Case Presentations
Shared Resources
Provide centrally organized capabilities in 2 new Shared Resources
2014 Registries 2016 Survey Research
Increase use or clientele in Shared Resources 2012 _____ 2017 _____
Research Impact
Total cancer-related publications 2012 – 426, 2014 ____ 2017 ____
Cancer-related in high-impact journals 2012 ___ 2014 ____ 2017 ____
Total of inter-programmatic collaborative publications 2012 - 47, 2014 ____ 2017 ___
Total of intra-programmatic collaborative publications 2012 – 121, 2014 ____ 2017
___
Scientists in Tumor Boards
2012 - 3 in 14_ tumor boards
2014 ___ in ___ tumor boards
2017 ___ in ___ tumor boards
End of Life
Patients with Advance Directives 2012 ___% 2014 ___% 2017 ___ %
Documentation of End of Life Discussions 2012 ___% 2014 ___% 2017 ___ %
Translation of Prevention Findings to Catchment Area
# of citizens involved
Diet and Obesity 2012 ___ 2014 ____ 2017 ____
Smoking 2012 ___ 2014 ____ 2017 ____
Sun Safety 2012 ___ 2014 ____ 2017 ____
Screening 2012 ___ 2014 ____ 2017 ____
Improve Patient Experience
Willingness to recommend to a friend 2012 ___% 2014 ___% 2017 ___%
Patient & Family Services Programs - # of people 2012 ___ 2014 ____ 2017 ____
Translate Scientific Discovery
Lead the Nation in Cancer
Prevention & Health Promotion
1a. Improve communication mechanisms
between investigators and clinicians to
promote translational oncology
2a. Expand research resources to support
translational and clinical science
3a. Use NCCC discoveries about personal
and environmental risk factors to reduce
cancer risk for communities
1b.Encourage team science to promote
multidisciplinary approaches
2b.Provide Cancer Center resources to remove
barriers to conducting Dartmouth investigatorinitiated clinical translational trials
3b..Use population based research in
cancer control to inform and optimize
primary care practices
1c.Encourage innovative approaches to
resolve key questions in basic science,
clinical science, and population science to
affect public health policy.
2c.Hire Strategically to support translational
research
Advance Scientific Discovery
Hire New Faculty
2012 – 2013 – 10 faculty appointments
2014 - 2015
2016 - 2017
3c. Discover novel approaches to prevent
or control cancer development
Deliver Patient-Centered Care
0a. Define specific populations and achieve
measurable advancement in their health status
by providing high value health care
0b. Achieve seamless coordination within NCCC,
among external partners, making us the highvalue health system of choice for our region
based on a Culture of Caring
0c.. Use quality and safety metrics, health
delivery science, and comparative effectiveness
to optimize patient outcomes
Increase Prouty Funding
2012 $2.6MM
2014 $3.0MM
2017 $3.5MM
Peer-Reviewed Funding
NIH-approved (incl. NCI) 2012 - $45.8MM 2014 ____ 2017 ____
NCI 2012 - $27.2MM 2014 ____ 2017 ____
Total – all sources 2012 - $61.7MM, 2014 ____ 2017 ____
Pilot Funding for Research
Develop Director’s Pilot Funding 2012 - 5, 2014 ____ 2017 ____
Increase Prouty Pilot funding grants 2012 - 7, 2014 ____ 2017 ____
Increase ACS pilot grants 2012 - 5, 2014 ____ 2017 ____
Promote Regional Leadership
Steward Resources
5a. Communicate NCCC findings to inform public
health policy on a regional and national level
6a. Focus on strengths in areas most likely to
impact cancer in humans
5b.Network NCCC providers to partner with
region-wide community-based services
6b.Facilitate communication among
investigators and promote faculty
development to maximize scientific discovery
.
5c.Use NCCC’s specialized services and
capabilities to provide region wide access to the
best cancer health care
6c.Optimize communication to increase
awareness of NCCC expertise and services
Center Vision
Strategic Goals
 Enhance our translational focus and disseminate trials
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regionally by hiring 2 physician investigators
Discover new imaging strategies and incorporate imaging
research into a broader spectrum of research by utilizing the
Surgical Innovation Center and Advanced Imaging Center
Develop anti-VISTA therapies by expanding clinical
immunotherapy group
Improve cancer outcomes in our catchment area by expanding
our behavioral research.
Address emerging issues in cancer care delivery by
comparative effectiveness research through increased
interaction with TDI
Expand ongoing efforts to build global health initiatives by
supporting pilot grants in this area.
Plans for Future Use
Pilot Projects
Recruitment (Current)
•
Cancer Control /
• Translational
Tobacco Policy
• Collaborative
•
Biostatistics
• Interventional
•
Quantitative
• Relevance to Strategic
Biomedical Sciences
Plan
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Cancer Mechanisms
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Early Phase Clinical
Development
Cancer
Immunotherapy