Transcript Natural product chemistry

Natural product chemistry
Identify different natural products
Synthesise your own perfume
Dr J White
• What is your impression of a chemist?
• Write down one job that a chemist
does?
Natural products
• What are they?
• Chemicals found in living things
• Where can you find them?
• What can you do with them?
Where can you find them?
• Plants (spearmint), animals, bacteria
carvone
Marine Natural products
• Gorgonian octacoral
• Octalactin A
How do you get them?
What you do with them?
Pharmaceuticals
Food additives
Fragrances
Task
• Here are a mixture of natural products
with common fragrances
• Match the fragrance to the natural
product
What does the organic chemist do?
• Marine life have only a small amount of the
active component.
• Pharmaceutical companies want to make
these compounds
– Big scale
– Cheap
– Safe
– Improve on nature
Building
• We have to look at the target structure and
create a strategy to build it.
• Check our big recipe book of reactions
• Building a car or baking a cake.
Task
• Watch video clip from bbc senses
• http://www.youtube.com/watch?v=7jYtpOlKs
TI
• How bad was the smell?
• We will make our own brand of fragrance
What you have to do
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Safety
Wear gloves & safety glasses
Mix different ratios of
base notes least fragrance
Middle notes
Top notes most volatile
We will judge how good the fragrance is.
Top
Eucalyptus
Lemon
Middle
geranium
lavender
Jasmine
Bottom
Patchouli
Ylang
ylang
Top
Middle
Bottom
Eucalyptus
lavender
Ylang
ylang
Lemon
geranium
Jasmine
Patchouli
Chemistry
Chemical
physics
Physics
Bio
Chemistry
Bio
physics
Biology
They look more like this
Chemists