Transcript Contact Allergen Avoidance Database

The Contact Allergen
Replacement Database
James A. Yiannias MD
Associate Professor of Dermatology
Mayo Clinic Scottsdale
Purpose
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To facilitate antigen avoidance
 Database generates list of skin care
products free of patient’s known allergens
 > 1,500 U.S. skin care products
Utility of Database
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Consider a patient who is patch test sensitive to
fragrance mix
 Patient has been educated how to avoid
fragrance, yet...
 Eczema persists since patient didn’t realize
– Cinnamic alc. & Balsam of Peru = Fragrance
– Unscented & fragrance free products don’t
assure elimination of fragrance
cross-reactors
How CARD Helps…

CARD recognizes cross-reactions &
synonyms and
– generates a comprehensive list of skin
care products free of all fragrance like
antigens!
Another eg:
Utility of CARD

Patient is imid urea & quat-15 sensitive
 Allergen avoidance reviewed
 Patient’s eczema persists-Pt didn’t realize that DMDM-Hydantoin
should be avoided
 Database recognizes cross-reactions & deletes
all products containing formaldehyde
releasers
Products in Database
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Soaps, Shampoos, Conditioners
Moisturizers
Sunscreens
Make-ups
All prescription topicals in PDR
All OTC topicals in OTC PDR
How Products Were Chosen

Hypoallergenic skin care product
lines (eg. Aveeno, Almay, many
others)
 Large companies with widely
available products
Database Maintenance

All product formulations are updated
continuously
 Products with formulas > 1 year are
deleted
Database Clinical Usage

In use clinically at Mayo Clinic for 6 years
and by American Contact Dermatitis
Society Members for more than 3 years
 Broad patient and physician acceptance /
endorsement
How to use CARD
…next 7 slides
www.contactderm.org
CARD