Transcript Going Viral

HPV Related Disease
Ginny Ryan
What Is HPV?
• The human papillomavirus is the most common
sexually transmitted infection in the U.S.
– 79 million Americans infected
• Transmitted through direct skin-to-skin contact
during vaginal, anal, or oral sex
• HPV infects both males and females and usually
causes no symptoms
• HPV can cause genital (and other) warts; the
more serious subtypes of HPV can cause cancer
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HPV and Cervical Cancer
• Cancer is a disease in which cells within the body
begin to grow and spread uncontrollably
• Cervical cancer starts in the cervix, which is the lower
end of the uterus
– 2nd most common cancer in women worldwide
– 10,300 new cases each year in U.S.
• HPV types 16 and 18 are responsible for the majority
of HPV-caused cancers and account for
approximately five percent of all cancers worldwide3
HPV Prevention
• HPV can be prevented
– Vaccination and abstinence are the only proven
effective ways to prevent infection
– Research has shown that correct and consistent
use of condoms MAY reduce the transmission of
HPV between sexual partners
• Vaccination could prevent 22,000 cancers
each year in the U.S.
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FDA Approved
Gardisil™
Cervarix™
• Protects against 4 subtypes
of HPV – 6, 11, 16, 18
• Approved for young males
and females, ages 9-26
• Approved in 2006 for
females, 2009 for males
• Approved for prevention of
genital warts, cervical and
anogenital cancers
• Protects against HPV
subtypes 16 and 18
• Approved for young
females only, ages 9-25
• Approved in 2009
• Approved for prevention of
cervical and anogenital
cancers
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Vaccines
• Three injections over a period of six months
• Best completed BEFORE any sexual activity
– Still useful if completed after
• Effective
• Safe
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Percent of adolescents receiving vaccine
Those least likely to
receive the vaccine…
–
–
–
–
Younger girls
African American girls
Hispanic girls
Girls from lower
income families
– Boys
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Effective
• Despite low vaccine uptake in U.S.
– HPV infection among teens↓50%; ↓88% in vaccinated
girls
– Expected to lead to decrease in cancers in the future
• In Australia
– Government-funded, school-based national Human
Papillomavirus Vaccination Program
– Estimated 70% of teens have received 3 doses
– Prevalence of HPV 6, 11, 16, 18 decreased from 29% to 7%;
genital warts have also decreased
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Safe
• 111 million doses distributed in U.S.
• Adverse events very closely monitored
• Vaccine Adverse Event Reporting System at CDC
include 390,800 events:
– 91% fainting, pain and swelling (non-serious)
– 9% serious (death (27), permanent disability,
hospitalization)
• No cause-and-effect relationship found
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Talk with Your Provider
• HPV vaccine is primary prevention
• It is still important for women to have routine
cervical screenings in order to detect any precancer (called secondary prevention) or
cancer in its earliest form (called tertiary
prevention)
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Thank You!
www.uihealthcare.org/womenshealth
www.facebook.com/UIWomensHealth
To schedule an appointment, call 319-356-2294
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