Transcript Drugs may be indirect to pathogenesis

Some human GPCRs involved in aging and certain age-related pathologies
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3-D Pie Chart
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orthosteric site
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(the VFT module)
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allosteric site
(the heptahelical domain)
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Such compounds might soon prove to be excellent
drugs to treat various diseases including
anxiety
Parkinson’s disease
depression
drug addiction
schizophrenia(精神分裂症)
osteoporosis(骨质疏松症)
new taste enhancers
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Limitations of the approach
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pharmacological
bridge
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Contents
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No consensus has been reached
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The patients have no respond
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Drugs may be indirect to pathogenesis
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Drug’s action is unexpected to its feature
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No consensus has been reached
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The patients have no respond
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Drugs may be indirect to pathogenesis
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Drug’s action is unexpected to its feature
Contents
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1
No consensus has been reached
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The patients have no respond
3
Drugs may be indirect to pathogenesis
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Drug’s action is unexpected to its feature
Contents
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No consensus has been reached
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The patients have no respond
3
Drugs may be indirect to pathogenesis
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Drug’s action is unexpected to its feature
Perspective
It is to be hoped that an admixture of new techniques
and strategies of genomics, proteomics, which enable to
work together with the ‘‘old’’ biochemical approaches.
multi-marker
biological treatment monitoring
large scale automated measures
biological differential diagnostic system
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Lunch time !!!
and don’t forget the
importance of GPCRs
Made by jason_wjb