Transcript Bari, 15 January 2008

CONVEGNO “ITALIAN FOOD FOR LIFE”
FIERA DI PARMA, 8 MAGGIO 2008
FEDERALIMENTARE
Servizi S.r.l.
FOOD & HEALTH
PILLAR COORDINATOR:
Dr. Andrea Borsari – Granarolo
FOOD & HEALTH
Pillar coordinator
Andrea Borsari – Granarolo
Working group
Daniele Del Rio – UniPr
Vincenzo Fogliano – UniNa
Riccardo Fortina - UniTo
Patrizia Hrelia – UniBo
Silvana Hrelia – UniBo
Renato Iori - CRA
Giuseppe Maiani/Cristina Scaccini - INRAN
Emanuele Marconi – UniMol
Lorenzo Morelli - Università Cattolica di Piacenza
Elisabetta Sanzini - ISS
Giulio Testolin - UniMi
Communication,
Training &
Technology Transfer
Food &
Health
Food
Quality &
Manufacturing
Food Safety
Food &
Consumer
Sustainable
Food Production
Food Chain Management
Parma, 8 maggio 2008
FOOD & HEALTH
OBIETTIVI GENERALI
Parma, 8 maggio 2008
GOAL 1.UNDERSTANDING BRAIN FUNCTION IN
RELATION TO DIET.
Research challenge 1:
Diet and individual nutrients / non nutrients / metabolites
influence on brain health and performance in all age
groups (from infants to ageing people). Study of the
mechanisms through which dietary components
modulate brain development, cognitive performance and
prevent ageing-associated cognitive decline.
Parma, 8 maggio 2008
GOAL 1.UNDERSTANDING BRAIN FUNCTION IN
RELATION TO DIET.
Deliverables of Research Challenge 1:
1. Molecular, cellular and system-level mechanisms behind
neuroprotective/ neurorescue effects against both cognitive
impairments and neurological degeneration in brain injury sequelae
by dietary compounds and bioactive components of foods.
2. Food impact on neurogenesis either during development or during
neurorecovery after impairing events.
3. Healthy ageing by nutritional strategies in childhood.
GOAL 1.UNDERSTANDING BRAIN FUNCTION IN
RELATION TO DIET.
Research challenge 2:
To study the relationship between diet, dysfunctional sleep and
metabolic/hormonal/ autonomic function, a key issue in the
development and progression to obesity.
Deliverable:
Diet, sleep, autonomic and metabolic function increase understanding
of the role of dysfunctional sleep in the obesity epidemics.
GOAL 2. UNDERSTANDING THE LINK BETWEEN DIET
AND METABOLIC FUNCTIONS (OBESITY AND
ASSOCIATED METABOLIC DISORDERS)
Research challenge 1:
Identifying nutrition patterns able to counteract the
obesity epidemic and to prevent the metabolic disorders
clustering in the metabolic syndrome and cardiovascular
disease also elucidating the effect of dietary compounds
on the functionality of target organs.
Parma, 8 maggio 2008
GOAL 2. UNDERSTANDING THE LINK BETWEEN DIET
AND METABOLIC FUNCTIONS (OBESITY AND
ASSOCIATED METABOLIC DISORDERS)
Deliverables of Research Challenge 1:
1. Understanding the interlinked effect of dietary
components on intestinal and adipose tissue endocrine
functions and their relation to metabolic regulation and
derangements;
2. Dietary interventions in individuals affected by metabolic
syndrome and/or type 2 diabetes;
GOAL 2. UNDERSTANDING THE LINK BETWEEN DIET
AND METABOLIC FUNCTIONS (OBESITY AND
ASSOCIATED METABOLIC DISORDERS)
Deliverables of Research Challenge 1:
3. Evaluation of the relationship between food composition,
structure, rheological properties and in vivo post-prandial
glucose metabolism for different cereal and starchy
ingredients;
4. Understanding signaling pathways triggered by food and
food components, aiming to identify positive signals for
the prevention of metabolic diseases.
GOAL 2. UNDERSTANDING THE LINK BETWEEN DIET
AND METABOLIC FUNCTIONS (OBESITY AND
ASSOCIATED METABOLIC DISORDERS)
Research challenge 2:
Defining the effects of diets and nutrients early in the life
and the role of nutrition in healthy ageing.
Establishing dietary practices in childhood that reduce
the risk of developing excess fat mass and metabolic
disorders later in life and tackling the nutrition-related
wasting diseases in the elderly population.
GOAL 2. UNDERSTANDING THE LINK BETWEEN DIET
AND METABOLIC FUNCTIONS (OBESITY AND
ASSOCIATED METABOLIC DISORDERS)
Deliverables of Research challenge 2 :
1. Prospective studies on the relationship between calcium intake and
fractures to assess the magnitude of increased fracture risk at
different calcium intake levels. Dietary factors maximizing or
decreasing the retention of dietary calcium.
2. Maternal and infant dietary recommendations for optimal metabolic
and bone health; good dietary practices that begin in childhood and
are followed throughout the life span.
GOAL 2. UNDERSTANDING THE LINK BETWEEN DIET
AND METABOLIC FUNCTIONS (OBESITY AND
ASSOCIATED METABOLIC DISORDERS)
Research challenge 3:
Developing tests to establish individual diets based on
the genetic heritage.
Deliverables:
1. Contribution of epigenetic events on chronic diseases
later in life and the contribution of nutrition;
2. Dietary interventions in individuals with genetic variants
involved in the regulation of key metabolic functions
(PPAR gamma, Apo E, Apo A5, CETP, UCP 2,
Adiponectin);
GOAL 2. UNDERSTANDING THE LINK BETWEEN DIET
AND METABOLIC FUNCTIONS (OBESITY AND
ASSOCIATED METABOLIC DISORDERS)
Deliverables of Research challenge 3:
3. Identification by nutrigenomics (transcriptomics and/or
proteomics) of the effects of specific food components
(for example vitamin D or Zinc) on metabolic and
inflammatory pathways linked to obesity and diabetes.
GOAL 3. UNDERSTANDING DIETARY EFFECTS ON
IMMUNE AND INTESTINAL FUNCTIONS.
Research challenge 1:
Establishing the role of intestinal microbiota on
biotransformation of food compounds active on immune
(GULT) and intestinal function.
Parma, 8 maggio 2008
GOAL 3. UNDERSTANDING DIETARY EFFECTS
ON IMMUNE AND INTESTINAL FUNCTIONS.
Deliverables of Research Challenge 1 :
1.
Assessment of health promoting potential of traditional
foods with regard to intestinal microbiota immune
function and gut health. Evaluation of the functional
properties of specific components/ingredients of
traditional foods;
2. Identification of dietary/microbiological factors that
improve the barrier function of the intestine and the
resistance to infections in specific population groups
(i.e.: elderly). Food and intestinal microbiota components
driving immunoresponse.
GOAL 3. UNDERSTANDING DIETARY EFFECTS
ON IMMUNE AND INTESTINAL FUNCTIONS.
Deliverables of Research Challenge 1 :
3. Determination of the effects of the intestinal microbiota
metabolites on the liver function (gut-liver- axis
hypothesis). Probiotics and prebiotics for liver health;
4. Consideration of possible interactions of potential
bioactive molecule with dietary macronutrients and effect
on absorption and biological activity.
GOAL 3. UNDERSTANDING DIETARY EFFECTS ON
IMMUNE AND INTESTINAL FUNCTIONS.
Research challenge 2:
Pregnant women and infant nutrition in relation to
immune (de)regulation during later life.
GOAL 3. UNDERSTANDING DIETARY EFFECTS ON
IMMUNE AND INTESTINAL FUNCTIONS.
Deliverables of Research challenge 2:
1. Determination of a healthy diet for pregnant women and with regard
to the newborn during early life, in order to optimize immune function
and intestinal microbiota in order to decrease the risk for allergy.
Nutrigenomic studies on the effect of nutrients on pediatric disease
risk reduction;
2. Improvement of the allergome databases of plant- and animalderived food, knowledge of allergen post-translational
modifications and allergenicity increase by additives or
contaminants, and persistence after cooking.
Detection of allergens derived from gastrointestinal or hepatic
metabolites.
GOAL 3. UNDERSTANDING DIETARY EFFECTS ON
IMMUNE AND INTESTINAL FUNCTIONS.
Deliverables of Research challenge 2:
3. Reduction of food allergens by crop selection and study
of food and pollen cross-reacting allergens under climate
changes and environmental conditions.
GOAL 4. UNDERSTANDING THE RELATIONSHIP
BETWEEN THE QUALITY OF ANIMAL PRODUCTS AND
THE QUALITY OF ANIMAL FEEDING.
Research challenge 1:
Delivering healthy animal products in diets for humans.
Deliverable:
Developing new food based strategies to optimise
human health and to reduce the risk of diet related
diseases when animal products are included in the diet.
GOAL 4. UNDERSTANDING THE RELATIONSHIP
BETWEEN THE QUALITY OF ANIMAL PRODUCTS AND
THE QUALITY OF ANIMAL FEEDING.
Research challenge 2:
Determining dietary factors (or new feeds) that can
improve animal performances and the final quality
of animal products.
Deliverable:
Understanding the dietary effects of some feeds
components on animal productions (meat, milk and
eggs), such as essential amino acids, physically effective
fibre, fatty acids, antioxidants, protein feeds,
etc.
GOAL 4. UNDERSTANDING THE RELATIONSHIP
BETWEEN THE QUALITY OF ANIMAL PRODUCTS AND
THE QUALITY OF ANIMAL FEEDING.
Research challenge 3:
Improve nutritional quality of aquaculture products by
dietary and breeding strategies.
Deliverables:
1. Elucidate the role of probiotics and plants antioxidants in
the different steps of fish feeding chain in order to
enhance the quality of aquaculture products
2. Understanding the potential of microalgae as source of
bioactive ingredients for manufacturing of healthy foods
and for fish feeding.
GOAL 5. VALORISATION OF HEALTHY PROPERTIES OF
TRADITIONAL AND INNOVATIVE FOODS BY THE
CHARACTERIZATION OF BIOACTIVE
COMPOUNDS/SUBSTANCES IN RAW MATERIALS AND FOODS.
Research challenge 1:
Bioactive compounds in traditional and innovative food
system.
Deliverables:
1. In vitro assay and biomarkers to predict in vivo
functionality of healthy food /diet;
2. Development of natural raw materials/ingredients
enriched in bioactive compounds.
Parma, 8 maggio 2008
GOAL 5. VALORISATION OF HEALTHY PROPERTIES OF
TRADITIONAL AND INNOVATIVE FOODS BY THE
CHARACTERIZATION OF BIOACTIVE
COMPOUNDS/SUBSTANCES IN RAW MATERIALS AND FOODS.
Research challenge 2:
Biological, nutritional and pharmacological properties of
the main components of Mediterranean diet.
Deliverables:
1. Identification, analysis and purification of specific
substances and bioactive compounds in Mediterranean
food diet;
2. Studies of in vitro, ex-vivo and in vivo models.
Parma, 8 maggio 2008
FOOD & HEALTH
CALENDARIO A MEDIO TERMINE
Parma, 8 maggio 2008
GRAZIE PER L’ATTENZIONE
http://www.federalimentare.it/ Attivita/ETP-Italia/ETP-FoodForLife-italia.asp