Transcript Special Skin Cells Make Melanin

Lesson 2
Special Skin Cells Make Melanin
body
tissue
epidermis
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melanocytes
epidermis
cells
How is melanin made inside the melanocytes?
Slide 2.1
Lesson 2
Melanin
Qu i c k T i m e ™ a n d a
T I F F (Un c o m p re s s e d ) d e c o m p re s s o r
a re n e e d e d t o s e e t h i s p ic t u re .
Skin Colors
Qu i c k T i m e ™ a n d a
T I F F (L Z W ) d e c o m p re s s o r
a re n e e d e d to s e e t h i s p i c t u re .
Qu i c k T i m e ™ a n d a
T I F F (U n c o m p re s s e d ) d e c o m p re s s o r
a re n e e d e d to s e e t h i s p i c t u re .
Cross Section of Skin Tissue
Melanocyte
Slide 2.2
Lesson 2
Looking inside a melanosome
Tyrosine
Oxygen
O O
DOPA
O
First step in making melanin:
Reaction between two molecules, one
tyrosine and one O2 to make DOPA
Slide 2.3
Lesson 2
Tyrosinase
(enzyme)
Tyrosine
O O
•
nuc
Oxygen
Skin cell
Slide 2.4
Lesson 2
Tyrosinase
(enzyme)
O
•
nuc
DOPA
Skin cell
Other enzymes turn help turn DOPA
Slide 2.5
into melanin.
Lesson 2
Lactose intolerance
• Cannot break down lactose, a disaccharide
found in dairy products
• Instead, bacteria in the intestine break down
the lactose, producing gas
• Most children can break down lactose
• Most adults in the world cannot break down
lactose - making them lactose intolerant
Slide 2.6
Lesson 2
Cells in Small Intestine
Break Down Lactose
Lactose
from diet
Lactose
brought
into
intestine
cells
small
intestine
intestine cells
Lactose
broken
down
How is lactose broken down in intestine cells?
Slide 2.7
Lesson 2
Looking inside small intestine cells
lactose
galactose
Small intestine cells
glucose
Slide 2.8
Lesson 2
Looking inside small intestine cells
lactase
Small intestine cells
lactose
Slide 2.9
Lesson 2
Looking inside small intestine cells
lactase
glucose
galactose
Small intestine cells
Slide 2.10
Lesson 2
Lactase
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Slide 2.11
Lesson 2
Protein Structure
Chain of
amino acids
Folded chain of
amino acids
amino acid
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Whole protein
Slide 2.12
Lesson 2
Protein Models
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Cartoon model
Space-filling model
Qu i c k Ti m e ™ a n d a
TIF F (L Z W ) d e c o m p re s s o r
a re n e e d e d to s e e th is p i c tu re .
Toober model
Slide 2.13
Lesson 2
Modeling Lactase
Qu i c k T i m e ™ a n d a
T I F F (L Z W ) d e c o m p re s s o r
a re n e e d e d t o s e e t h i s p i c t u re .
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are needed to see this picture.
Slide 2.14
Lesson 2
Key to Toobers
Blue=positive charge (+)
K, R, H
Red=negative charge (-)
D, E
Yellow=hydrophobic
A, V, L, I, P, M, F, W
Green=hydrophilic
G, S, T, N, Q, Y
White = cysteine
C
Slide 2.15