Transcript Chirality in Pharmaceutical Synthesis

Chirality in
Pharmaceutical Synthesis
Task - Create a PowerPoint to include:
• Examples of molecules indicating any chiral carbons.
• Examples of pharmaceuticals and diagrams of their 2
optical isomers.
• Thalidomide drug – how the 2 optical isomers show
different pharmacological activities.
• Explanation of why natural molecules usually only have
one optical isomer.
• Methods for synthesising molecules of only one type of
optical isomer (to avoid situations like with
Thalidomide)
• Explanation of why Ibuprofen can be sold as a mixture
of optical isomers safely.