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INTRODUCTION TO
AUTOMOMIC PHARMACOLOGY:
Part I: Why study autonomic pharmacology?
Autonomic Pharmacology
is Rewarding!!
LOGICAL
CLINICALLY
RELEVANT
Autonomic Pharmacology is Logical
Mechanism
of Drug Action
+
Anatomical,
Physiological &
Neurobiological
Information
Predict
Effects of Drugs
Autonomic Pharmacology is Logical
Drug A blocks
receptors for
neurotransmitter X
+
Nerves to organ Y
release neurotransmitter X,
and X increases
the activity of organ Y
Drug A decreases
activity of
organ Y
Autonomic Pharmacology
is Clinically Relevant
Autonomic drugs are used for the
treatment of
Angina
Autonomic drugs are used for the
treatment of
Heart Failure
Autonomic drugs are used for the
treatment of
Alzheimer’s Disease
Autonomic drugs are used for the
High Blood
Pressure
treatment of
Autonomic drugs are used for the
treatment of
Benign Prostatic Hypertrophy
Autonomic drugs are used for the
treatment of
Anaphylactic Shock
Autonomic drugs are used for the
treatment of
Septic Shock
Autonomic drugs are used for the
treatment of
Asthma