Transcript Digestive

Digestion
Digestion

Prepares food for cellular intake
Nutrients must be small enough to be
absorbed
 Nutrients broken down by mechanical and
chemical means

Occurs in digestive tract
 Food moved by peristalsis

The Mouth to the Small
Intestine

Digestion begins in mouth
Mastication breaks up food
 Tongue and palate mix in saliva
 Moistened food passed:

• Into pharynx → through esophagus →into stomach

Churning of stomach further breaks down food by:

Mixing with enzyme pepsin and HCl
The Mouth to the Small
Intestine (con’t)

Partially digested food passes through pylorus
into duodenum

Digestion completed after passing through
other parts of small intestine (jejunum and
ileum)

Digested nutrients absorbed into circulation
Accessory Organs
Accessory Organs

Liver


Gallbladder


Secretes bile to break down fats
Bile stored here until needed
Pancreas

Produces mixture of digestive
enzymes
The Large Intestine



Undigested food, water, digestive juices
Begins with cecum
Colon twists and turns:






Ascending colon
Transverse colon
Descending colon
Water reabsorbed, feces formed
Waste material passes into sigmoid colon
Waste stored in rectum; eliminated through anus
Clinical Aspects of
Digestion


Gastrointestinal tract
Infection


Can be caused by variety of organisms
Ulcers



Lesion of skin or mucous membrane
Marked by inflammation or tissue damage
Can be diagnosed by:
• Endoscopy
• Barium study (Radiography with contrast
medium)
Cancer


Colon and rectum most likely affected
area
Risk factors:





Diet low in fiber, high in fat
Heredity
Chronic inflammation of colon (colitis)
Polyps often become cancerous
Symptom: bleeding into intestine
Cancer (con’t)
Internal observations performed with
endoscopes
 Treatment may require surgical removal
of portion of GI tract

May create a stoma for waste elimination
 Surgery is called –ostomy, with root
named for involved organ (e.g. colostomy)

Obstructions

Hernia


Pyloric stenosis


Protrusion of organ through abnormal
opening
Opening between stomach and small
intestine too narrow
Intussusception

Slipping of part of intestine into part
below
Obstructions (con’t)

Volvulus


Ileus


Intestinal twisting
Intestinal obstruction caused by
lack of peristalsis
Hemorrhoids

Varicose veins in rectum
Appendicitis

Results from infection of appendix

Surgery required to:
Avoid rupture
 Prevent peritonitis

Inflammatory Bowel
Disease

Crohn disease



Chronic inflammation of intestinal wall
segments, usually ileum
May causes:
• Pain
• Diarrhea
• Abscess
• Formation of fistula
Ulcerative colitis
 Continuous inflammation of colon lining,
usually rectum
Hepatitis


Inflammation of the liver
More than six types of viral infections

Hepatitis A
• Spread by fecal-oral contamination

Hepatitis B
• Spread by blood and other body fluids

Vaccines available for Hepatitis A and B
Cirrhosis


Chronic liver disease mainly caused by excess
consumption of alcohol
Characterized by:





Hepatomegaly
Edema
Ascites
Jaundice
As it progresses:



Splenomegaly
Internal bleeding
Brain damage
Gallstones

Cholecystitis


Cholelithiasis



Presence of stones in gallbladder
Usually associated with cholecystitis
Diagnosed by:




Inflammation of gallbladder
Ultrasonography
Radiography
Endoscopic retrograde
cholangiopancreatography
Treatment may involve:


Drugs to dissolve stones
Cholecystectomy
Pancreatitis
Inflammation of pancreas
 May result from:

Alcohol abuse
 Drug toxicity
 Bile obstruction
 Infections
 Other causes


Disease often subsides with only
treatment of symptoms