Transcript Digestive
Digestion
Digestion
Prepares food for cellular intake
Nutrients must be small enough to be
absorbed
Nutrients broken down by mechanical and
chemical means
Occurs in digestive tract
Food moved by peristalsis
The Mouth to the Small
Intestine
Digestion begins in mouth
Mastication breaks up food
Tongue and palate mix in saliva
Moistened food passed:
• Into pharynx → through esophagus →into stomach
Churning of stomach further breaks down food by:
Mixing with enzyme pepsin and HCl
The Mouth to the Small
Intestine (con’t)
Partially digested food passes through pylorus
into duodenum
Digestion completed after passing through
other parts of small intestine (jejunum and
ileum)
Digested nutrients absorbed into circulation
Accessory Organs
Accessory Organs
Liver
Gallbladder
Secretes bile to break down fats
Bile stored here until needed
Pancreas
Produces mixture of digestive
enzymes
The Large Intestine
Undigested food, water, digestive juices
Begins with cecum
Colon twists and turns:
Ascending colon
Transverse colon
Descending colon
Water reabsorbed, feces formed
Waste material passes into sigmoid colon
Waste stored in rectum; eliminated through anus
Clinical Aspects of
Digestion
Gastrointestinal tract
Infection
Can be caused by variety of organisms
Ulcers
Lesion of skin or mucous membrane
Marked by inflammation or tissue damage
Can be diagnosed by:
• Endoscopy
• Barium study (Radiography with contrast
medium)
Cancer
Colon and rectum most likely affected
area
Risk factors:
Diet low in fiber, high in fat
Heredity
Chronic inflammation of colon (colitis)
Polyps often become cancerous
Symptom: bleeding into intestine
Cancer (con’t)
Internal observations performed with
endoscopes
Treatment may require surgical removal
of portion of GI tract
May create a stoma for waste elimination
Surgery is called –ostomy, with root
named for involved organ (e.g. colostomy)
Obstructions
Hernia
Pyloric stenosis
Protrusion of organ through abnormal
opening
Opening between stomach and small
intestine too narrow
Intussusception
Slipping of part of intestine into part
below
Obstructions (con’t)
Volvulus
Ileus
Intestinal twisting
Intestinal obstruction caused by
lack of peristalsis
Hemorrhoids
Varicose veins in rectum
Appendicitis
Results from infection of appendix
Surgery required to:
Avoid rupture
Prevent peritonitis
Inflammatory Bowel
Disease
Crohn disease
Chronic inflammation of intestinal wall
segments, usually ileum
May causes:
• Pain
• Diarrhea
• Abscess
• Formation of fistula
Ulcerative colitis
Continuous inflammation of colon lining,
usually rectum
Hepatitis
Inflammation of the liver
More than six types of viral infections
Hepatitis A
• Spread by fecal-oral contamination
Hepatitis B
• Spread by blood and other body fluids
Vaccines available for Hepatitis A and B
Cirrhosis
Chronic liver disease mainly caused by excess
consumption of alcohol
Characterized by:
Hepatomegaly
Edema
Ascites
Jaundice
As it progresses:
Splenomegaly
Internal bleeding
Brain damage
Gallstones
Cholecystitis
Cholelithiasis
Presence of stones in gallbladder
Usually associated with cholecystitis
Diagnosed by:
Inflammation of gallbladder
Ultrasonography
Radiography
Endoscopic retrograde
cholangiopancreatography
Treatment may involve:
Drugs to dissolve stones
Cholecystectomy
Pancreatitis
Inflammation of pancreas
May result from:
Alcohol abuse
Drug toxicity
Bile obstruction
Infections
Other causes
Disease often subsides with only
treatment of symptoms