Transcript Sickle Cell Anemia

SICKLE
CELL
Also Know As:
Sickle Cell Anemia, Hemoglobin S
Disease, and Sickle Cell Disorder
By:
Hannah Franklin, Mallory James, Chris Daniels,
Chris Ishman
Sickle Cell Anemia
This disease was discovered in 1910
when a patient complained of a series
of pain episodes and symptoms of
anemia. Dr. James B. Herrick was not
interested in his case until Dr. Ernest Irons
found sickle shaped blood cells. This disease got
its name because of the sickle shape of the
infected blood cell.
Genetic Disorder
Sickle cell is an anemia and it is genetically
passed down and sickle cell anemia is caused
by abnormal hemoglobin or mutated HBB
genes.
Symptoms and Effects
Sickle Cell is an abnormal hemoglobin that
blocks blood flow. The effects of this disorder
are;
-Fatigue caused by anemia
-Yellowing of the skin
-High stress levels
-Swelling of the hands and feet
-Fever
Diagnoses
Doctors determine if a person has Sickle Cell by performing a blood test.
for newborns, blood from a heel prick is collected in “spots” on a special
paper. The Hemoglobin from this blood is then analyzed in special labs.
if a baby is found to have Sickle Cell, health providers form a special
follow-up newborn screening. the child is always retested to be sure the
diagnoses is correct.
To diagnose Sickle Cell, doctors will perform a blood test.to check for
HemoglobinS- the defective form of Hemoglobin that underlies Sickle
Cell Anemia. It can also be diagnosed in an unborn baby by sampling
some of the fluid surrounding the baby in the mother’s womb to look
for the Sickle Cell gene.
Prognoses Of individual
The average life expectancy is now in the mid 40 years of age range.
precautions/limitations they face is in exercise. the metabolic changes
imposed by exercise may indicate sickling and vaso-occlusive episodes.
This disorder impacts a person’s whole life. things as simple as sipping a
cold drink and swimming can trigger pain. In adults, stress can also cause
pain.
This disorder impacts family members lives a lot. This is because you have
to make sure the child has his/her medicine at the right time, making sure
they are kept hydrated, that they are kept warm and dry, and much, much,
more.
Treatments/ Medications
Available
Current treatments to treat Sickle Cell are antibiotics, pain relievers,and
hydroxyurea. These drugs are taken to try to prevent painful crises, fight
off infections, such as Pneumonia, and help with pain associated with
Sickle Cell. Current treatments of symptoms include OTC medicine,
heating pads, fluids, and pain-controlling medicines.Common ways to
treat crises are with acetaminophen, nonsteroidal anti-inflammatory
drugs(NSAIDS), and narcotics.
In the past doctors have learned what cause it, now you can treat it , and
how to potentially cure it.
With SCD, genes therapy is possible and has been done but only with
people on trials so far.
Current Research
The children’s hospital of philadelphia has been
researching more about sickle cell. They have
been trying to find a cure for this seemingly
incurable disease Their next goal is to find a
cure for disorders that are similar to sickle cell,
tumors, and such.
Tionne Watkins
Tionne Watkins was first diagnosed with a brain
tumor in 2006. Then after the brain tumor was
removed she was diagnosed with sickle cell
anemia. Tionne was in and out of hospitals for
her disease. Instead of letting this disease
discourage her she reached out to the other
who were infected. Soon after she became a
speaker for anyone who was infected by this
disease.
Bibliography
⬜ http://pbsblood.weebly.com/other-names.html
⬜ www.nhlbi.gov/health-topcs/sca/diagnosis
⬜ www.chop.edu/centers-programs/sickle-cell-center
⬜ www.m.webmd.com/ain-mangement-sickle-cell-disease
⬜ www.mayoclinic.org/diseases-conditions/sickle-cell-
anemia/basics/tests-diagnosis/con-20019348
⬜ www.sicklecelldisease.org/index.ctm?pages=faq
⬜ Interview with Chien-Kuang Ding
guest lecture
Duke University: Genetics outreach
Durant road middle school
February 23, 2016