Transcript Extra Pedigree Problem - Winona State University

Color Blindness (#2)
Sickle Cell Anemia Affects the B-chain of Hemoglobin. It is a genetically
inherited disease, and is seen commonly in Africa. Sickle Cell Disease is a
group of inherited red blood cell disorders. Normal red blood cells are round like
doughnuts, and they move through small blood tubes in the body to deliver
oxygen. Sickle red blood cells become hard, sticky and shaped like sickles used
to cut wheat. When these hard and pointed red cells go through the small blood
tube, they clog the flow and break apart. This can cause pain, damage and a
low blood count, or anemia.
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Sickle Cell
Normal Cell
Symptoms of Sickle Cell Anemia
pain episodes
strokes
increased infections
leg ulcers
bone damage
yellow eyes or jaundice
early gallstones
lung blockage
kidney damage and loss of body water in urine
painful erections in men (priapism)
blood blockage in the spleen or liver (sequestration)
eye damage
low red blood cell counts (anemia)
delayed growth
Sickle Cell Anemia #9
Myotonic Dystrophy (#2)
Hemophila #4
What is CF?
Cystic fibrosis (CF) is a life-threatening
genetic disease affecting approximately
30,000 people in the United States. For
people with the disease, a defective gene
causes the body to produce a faulty protein
that leads to abnormally thick, sticky mucus
that clogs the lungs and can result in fatal
lung infections. The mucus also obstructs
the pancreas, causing difficulty for a person
to absorb nutrients in food and can block
the bile duct in the liver, eventually causing
permanent damage in approximately six
percent of people with CF.
Cystic Fibrosis (#25)
Cystic Fibrosis (#49)
Pedigree (#1)
Pedigree #2