Transcript Slide 1
Update on Childhood Obesity
Barbara Thompson, MD
Pediatric Endocrinology
Mary Bridge Children’s Hospital
http://static.howstuffworks.com/gif/childhood-obesity-bmi.gif
MHS/MMA Pediatric Well Child Checks
4/1/12-3/31/13
16000
14102
14006
14000
12000
10000
Well Child Checks
BMI recorded
8000
Overweight/Obese
6000
4462
4000
2000
0
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Assessment of Obesity
• BMI kg/m2
• Index of adiposity
• Correlates with markers of secondary complications of
obesity: blood pressure, lipids, and lipoproteins
BMI
• >95%ile for age and sex:
• These children should undergo an evaluation
• Also have a significant likelihood of persistence of
obesity into adulthood
• 85-95%ile: at risk for obesity
BMI Curves
The Medical History
• Identifies modifiable lifestyle behaviors
• Assessment of current and future risks for medical co
morbidities
• Assessment of patient and family’s readiness to
change
• A history of poor growth despite weight gain more
likely to suggest hormone disorders or genetic
syndromes
Singe gene disorders
• Prader-Willi, Bardet-Biedl, Alstorm and Cohen
syndromes
• Relatively rare
• Genetic testing may be indicated when specific
findings are present
Hypothyroidism
• Frequently a concern of parents but does not usually
cause severe obesity
• Usually has cessation of linear growth
• Extremely unlikely in the tall obese child
Complications of Obesity
• Orthopedic: SCFE, Blount’s disease
• Neurologic: pseudotumor cerebri
• Respiratory: Obstructive sleep apnea, obesity
hypoventilation syndrome
• Endocrine: PCOS, Diabetes
• Cardiovascular: Hypertension, dyslipidemia
• GI: NAFLD
Who to evaluate?
• BMI <85%ile: not at risk for overweight
– Diet and exercise counseling especially if parents are
obese
BMI 85-95%ile: At risk for overweight
Evaluate family history, blood pressure, cholesterol, degree
of change in BMI and family’s concern about weight
Evaluation of Co-Morbidities
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Sleep and Respiratory
Gastrointestinal
Endocrine Disorders
Blood pressure
Lipids
Orthopedic Disorders
Depression
Sleep/Respiratory
• Prevalence may be >50% among adolescents
with severe obesity
• Ask about snoring and daytime somnolence
• Obstructive sleep apnea may occur in the
absence of enlarged tonsils
• May lead to RVH and pulmonary hypertension
• Diagnosis made by polysomnography
NAFLD
• Most common cause of liver disease in children
• Includes simple steatosis, steatohepatits, fibrosis,
and cirrhosis resulting from fatty liver
• Generally asymptomatic but may have vague,
recurrent abdominal pain
• Screen with routine abdominal exams and AST/ALT
• Initial treatment is weight loss and improving insulin
resistance
• GERD, gallstones and constipation also common in
obesity
Type 2 Diabetes
• The rise in type 2 is occurring world wide in parallel
with an increase in childhood obesity
• NHANES- 29% of self-reporting adolescents with
diabetes (12-19y) had type 2
• In a group without diabetes 11% had impaired fasting
glucose
Risk Factors
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Overweight
Family History
Ethnicity
Conditions with insulin resistance
Who should we screen?
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Screening recommendations for type 2 diabetes mellitus (T2DM) in children and
adolescents
Overweight status
Body mass index 85th percentile for age and gender, Weight for height 85th
percentile, Weight 120 percent of ideal for height
Plus any two of the following risk factors:
1. Family history of T2DM in a 1st or 2nd degree relative
2. High-risk race/ethnicity African American, Hispanic, Asian Pacific Islander,Native
American
3. Signs of insulin resistance on physical examination or conditions associated with
insulin resistance : Acanthosis Nigricans, Hypertension, Dyslipidemia, Polycystic
ovary syndrome
Begin screening at age 10 years or at onset of puberty if this occurs less than 10 years
old. Repeat screening every 2 years
Diabetes Care. 2006 Feb;29(2):212-7.
How should we screen?
• FPG or OGTT?
• The ADA recommends measuring a fasting plasma
glucose (FPG) as the preferred method of screening
because it is more convenient, less expensive, and less
invasive than the oral glucose tolerance test (OGTT).
• An FPG 126 mg per dL is consistent with the diagnosis
of diabetes
• An FPG 100 mg/dL to 125 mg/dL demonstrates impaired
fasting glucose (IFG) and is consistent with the diagnosis
of pre-diabetes. Patients with IFG should undergo an
OGTT.
Criteria for diagnosis
Normoglycemia IFG/IGT
Diabetes
FPG <100mg/dl
FPG>100 and
<126
FPG>126
2 hour PG <140
2 hour PG 140200
2 hour PG >200
Symptoms of
diabetes and
random glucose
>200
Metabolic Syndrome
• Constellation of metabolic derangements that include
obesity, insulin resistance, dyslipidemia, and
hypertension
• NHANES defined metabolic syndrome as waist
circumference >90th %ile, BP>90th %ile,
FPG>110mg/dL, HDL and triglycerides >90th %ile
• Predicts both type 2 diabetes mellitus and premature
coronary artery disease
Hypertension
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Evaluation based on gender, age and height
Hypertension systolic and/or diastolic >95th percentile
Prehypertension 90-95th percentile
Start with lifestyle changes
May need ambulatory blood pressure monitoring
Dyslipidemia
• Fasting lipid profile should be obtained when BMI>85th
percentile
• Total cholesterol levels of <170 mg/dL are acceptable
and >200 mg/dL is high
• LDL <110 mg/dL, >130 mg/dL is high
• Start with dietary changes
• Consider treatment after 6 months of therapy:
Age>10y, LDL >160mg/dl
Psychiatric Disorders
• Depression may precede or result from an obesity
• Look for anxiety, body dissatisfaction, eating disorders
• Sexual and physical abuse increase the risk of severe
obesity
Orthopedic Disorders
• Blount disease: painless bowing of the lower extremity,
dx with anteroposterior radiographic views of the
affected knee obtained while standing
• SCFE: hip or knee pain and pain with walking,
impaired range of motion, b/l frog-leg radiographic
views
Summary of Medical Screening
• History: BMI change
• Meds: medications that may affect weight
• ROS: snoring/sleep problems, abd pain,
menstrual irreg, hip, knee, or leg pain, polyuria,
thirst, depression
• Family Hx: obesity, T2DM, HTN, lipid
abnormalities, heart disease
Primary Care Laboratory Assessment
BMI>95%ile
Tests
>85%ile with no risk factors
Fasting lipid levels
>85-95%ile with risk factors
Fasting lipid levels, AST and ALT, fasting
glucose
>95%ile
Fasting lipid levels, AST and ALT, fasting
glucose
Pediatrics, December 2007
Weight….Let’s talk
Peggy Norman, MS,RD,CDE
Pediatric Weight and Wellness Program
Coordinator
Mary Bridge Children’s Hospital
Weight…. Let’s LISTEN
• 20 years of adult obesity care
– 5000 hrs listening to overweight adults
– 3000 adult group hours
– Reviewed 1000s for food diaries
• 15 years with pediatrics
– 1000 hrs listening to parents of overweight children
– 1000 hrs listening to overweight teens and children
– 2000 family group hours
Stages of Intervention
• Stage 1: Primary care
• Stage 2: Structured weight management
• Stage 3: Multidisciplinary Intervention
• Stage 4: Tertiary Care Intervention – VLCD, bariatric
surgery, medications
AAP – Expert Committee Recommendations Regarding the Prevention, Assessment and Treatment of child and Adolescent
Overweight and Obesity (Barlow 2007)
MHS/MMA Pediatric Well Child Checks
4/1/12-3/31/13
16000
14102
14006
14000
12000
10000
Well Child Checks
BMI recorded
8000
Overweight/Obese
6000
4462
4000
2000
0
1
Pediatric Weight and Wellness Program
Participation (4/1/12-3/31/13)
2500
2186
2000
Identified as Obese
Referrad to PWW
1500
Assessed
1000
500
Attend Group
488
97
0
1
57
WHAT is 5210?
Ready, Set, Go! 5210 program interventions
center on the use of the common message of
“5‐2‐1‐0”. These behaviors are supported by science
and endorsed as recommendations by
medical professionals:
READY, SET, GO! 5210
Continuing the Call to Action for Obesity Prevention
READY, SET, GO! MISSION
Ready, Set, Go! 5210 mission is to increase physical
activity and healthy eating among each of the six
sectors that influence youth and families;
1. Schools
2. After School
3. Early Childhood
4. Health Care
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6.
Workplace
Community
7.
And….Faith Communities
Consistent Message for Every Child
• Every family hears the health message at well child
checks ( all 14,103 plus other opportunities?)
• Discuss healthy growth for age – using BMI
• Connect 5210 message to future health
Consistent Messaging from Providers
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Provider is committed to 5210 message
Practice is committed to 5210 message
Reflected in the office environment
Involved in community leadership
5210 SmartPhrase: type .5210 to
drop into Patient Instructions
Child with weight concern
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Ask permission to talk about weight
Avoid shame , blame
Acknowledge that there are no simplistic solutions
Use the 5210 goals to agree on at least one behavior
change
• Refer to stage 2 or 3
• There is NO ONE “RIGHT WAY” to TALK about
WEIGHT
Referral to Family Wellness Program
• Family receives packet that frames complexity of
weight by addressing beliefs, parenting skills and
environment.
• 5210 message reinforced
• Family contacted by letter to encourage them return
packet at 3 month point.
• Family knows a resource exists
Stage 3: Family Wellness Program
• Pre Assessment Questionnaire and lab work required
• In-depth Medical Assessment
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Medical evaluation
Nutrition and Activity evaluation
Psychosocial evaluation
Goal setting
• Invitation to year long intervention
Year Long Intervention
• Quarterly rolling starts
• 3 week intensive “ Basic Core"
• Monthly for 1 year
• Opportunities to connect with each other between
groups on own communities
• Weekly swim group
• Gift Card incentive for participation
• 85% qualify for max financial assistance
Case Profiles - Teens
Kayla - 13
5’ 11.5” 269 #
BMI 36.59 99.41%
• Hypertriglyceridemia
• High life stressors
Program: over 18 months
Brandon -15
5’5.75” 300#
BMI 48.8 99.82%
• Intermittent Asthma
• Low life stressors
Program: 18 months
• 23 visits
• 32 mental health visits
Fitness/habit measures stable
• 18 visits
+ 30 lbs
6’ 0.5” 297#
BMI 40.68 99.52%
Fitness/habit measures improved
- 30 lbs
• 5’7” 267#
• BMI 41.81 99.74%
Thank-you
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