Transcript Document

A Tour of the Cell
Cell Biology
Outline
• Cell Structure and Organelles
• Electron micrographs, figures and function
• Cell Molecular Components
Structure of
Animal Cells
Cell Video
Protection and
Controlling Entry
Cell Membrane
Cell Membrane Composition
• Plasma membrane encloses cell and cell
organelles
• Made of hydrophobic and hydrophillic
components
– Semi-permeable and fluid-like
– “lipid bilayer”
Cell Membrane Composition
• Integral proteins interact with “lipid bilayer”
– Passive transport pores and channels
– Active transport pumps and carriers
– Membrane-linked enzymes, receptors and
transducers
• Sterols stabilize the lipid bilayer
– Cholesterol
Cell Wall
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Function: provides
support and
protection to the cell
membrane
Found outside the
cell membrane in
plant cells
Cellulose is
porous, rigid
and strong
Control of the Cell
Cell Organelles
•
Nucleus
Nickname:“The Control Center”
Function: holds the DNA
Parts:
Nucleolus: dark spot in the middle of the nucleus that
helps make ribosomes
Chromatin: loosely coiled DNA (cells not dividing)
two types – hetero__ –dark
- eu__ - light
Organelles that Provide
Energy
•Mitochondria
–Double membrane
–Mitochondrial (maternal) DNA,
–replicates independently from the cell
“Power House” of the cell
•Food converted into energy
–Adenosine triphosphate (ATP)
•Consumes Oxygen, produces CO2
Chloroplast
Nick name: Sugar Daddies
Function: traps energy from
the sun to produce food for the
plant cell
Green in color because of chlorophyll, which is a green
pigment
Double membrane structure
Unique DNA, replicates independently from the cell
Packaging and
Receiving
• Endoplasmic Reticulum (ER)
– Site where cell membrane and
exported material is made
– Rough ER (+ Ribosomes)
• Make proteins to be shipped out
– Smooth ER
Make lipids to be shipped out
Ribosomes
-sites of protein synthesis.
-not membrane-bound
- consists of a small and larger subunit,
- consists of ribosomal RNA (rRNA) and some 50 structural
proteins.
-Bound ribsosomes make proteins for export, non-bound
ribosomes make proteins for internal use
-Most plentiful organelle in the cell
Lysosomes:
circular, but bigger than ribosomes
Nickname: “Clean-up Crews”
Function: to break down food into particles the
rest of the cell can use and to destroy old
cells
Intracellular digestion
Releases nutrients
Breakdown of waste
Autolysis
Self-destruction of damaged cells:
–auto = self, lysis = break
–lysosome membranes break down
–digestive enzymes released
–cell decomposes
–cellular materials recycle
Golgi Complex/Apparatus
Nickname: The shippers
Function: packages, modifies, and transports
materials to different location inside/outside of
the cell
Appearance: stack of pancakes
Note the direction of the flow
Of the material into the cis and
Out the trans.
Vessicles
•
Peroxisomes
–
•
Hydrogen Peroxide generated and degraded to detoxify the
cell
Vessicles
–
•
Material transport
Vacuole
-
•
stores water
Plastids
-
Leucoplasts, aka amyloplasts store starch, protein or oils.
Chromoplasts store bright color pigments
Inter mediate filaments
Microfilaments
Microtubules
Structural proteins for shape and
strength
Microfilaments
– Thin filaments composed of the protein
actin:
provide additional mechanical strength
interact with proteins for consistency
Pairs with thick filaments of myosin for muscle
movement
Intermediate
– Mid-sized between microfilaments and
thick filaments:
durable (collagen)
strengthen cell and maintain shape
stabilize organelles
stabilize cell position
Microtubules
–Large, hollow tubes of tubulin protein:
attach to centrosome
strengthen cell and anchor organelles
change cell shape
move vesicles within cell (kinesin and
dynein)
form spindle apparatus
Form cilia and flagella
Centrioles in the Centrosome
Centrioles form
spindle apparatus
during cell division
Centrosome:
cytoplasm
surrounding
centriole
Cell Adhesion
Gycocalyx
-vecro-like ogliosaccharides that bind
and hold to other cells
Tight Junctions
- seal/adhere cells together
Adherens Junctions
- actin filaments that bind and hold
cells together
Gap Junction
-trans-cellular protein channels
Desmosome
-proteins the anchor intermediate filaments
from neighbouring cells together