Transcript Cancer Prevention - Steven Chaney 2014

Cancer Prevention
Steve Chaney, PhD, Cancer researcher
Barbara Lagoni
Steve Chaney, PhD
• Cancer research program for 37 years.
• Awarded almost $9 million dollars in grants
and contracts for his research.
• Internationally known for his research on the
biochemistry of platinum anticancer
drugs and their interactions with
cellular DNA.
• He helped develop a drug that represents a
major advance in the treatment of
colon cancer and was a featured
speaker at 6 international symposia
on platinum anticancer drugs.
• Awarded the “Excellence in Teaching
Lifetime Achievement Award” by the
Academy of Educators, University of
N Carolina Medical School
Incidence of Cancer
1.7 million new cases diagnosed in 2013
580,000 deaths
1,600/day
But good news is …
Cancer deaths are declining.
Top Causes of Cancer Deaths
Men
• Lung
• Prostate
• Colorectal
Women
• Lung
• Breast
• Colorectal
•15 different cancers are related to tobacco use
including, nasopharynx, lung, kidney, myeloid leukemia,
•1600 people die each day in US
•1 out of every 4 deaths is from cancer
• Closing in on heart disease as #1 cause of death in US
• 1 in 3 women and 1 in 2 men will be diagnosed with
cancer in their life-time
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Most Cancer is Not Genetic
• This year, more than 1.7 million Americans and
more than 10 million people worldwide are
expected to be diagnosed with cancer, a disease
commonly believed to be preventable.
• Only 5–10% of all cancer cases can be
attributed to genetic defects.
• The remaining 90–95% have their roots
in the environment and lifestyle.
PubMed Pharmaceutical Research 9/2008
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Cancer is Preventable
Over 60% of cancer deaths could be
preventable according to the 2008 ACS
annual report, Cancer Prevention and Early
Detection Facts and Figures
30% caused by tobacco use and
30% attributed to poor nutrition, physical
inactivity, overweight, and obesity
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Many Risk Factors For
Cancer We Can Control
Don’t use tobacco
Maintain healthy weight
Get serious about a healthy diet
 Avoid bad fat
 Avoid sugar
 Eat lots of vegetables and fruits ( 6 to 10/day )
Exercise
Supplement with nutrients
help reduce cancer risks.
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that
3 Stages of Cancer
Initiation
Promotion
Progression
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Stage One – Initiation
DNA is damaged-- Precancerous cells
form …mostly caused by free radicals
& compounds that stick to our DNA
such as:
• Cigarette smoke and polluted air
• Carcinogens in our food (artificial
flavorings, colorings, preservatives )
• Benzopyrenes from grilling
• Sodium nitrate/ nitrites
• Aflatoxins in peanuts & corn ( beware
organic peanut butter or natural
peanut butter )
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Preventing Initiation
• Fiber – flush toxins out of your system before they
have a chance to damage cells
• Anti-oxidants are needed to protect DNA from
damage & to neutralize free radicals
• Diet heavy in vegetables /fruits
• Vitamins C, E, CarotoMax , FlavoMax,
• Vivix -- polyphenols
• Detoxification pathways need to activated
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Cabbage family vegetables ( sulfuraphanes )
Liver DTX
FlavoMax
Vivix – polyphenols turn on DNA repair & detox
pathways in the liver
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Need FULL SPECTRUM of all Antioxidants
… working together
• Studies that try to isolate single
vitamins … just beta carotene or
pure alpha tocopherol ( Vit E)
always conclude … “vitamins don’t
work”
• Pure alpha tocopherol interferes
with gamma, delta, beta and all the
other tocopherols.. Which have
important benefits that alpha
doesn’t have.
• Beta Carotene study .. Pure beta
carotene will interfere with
absorption of the other essential
carotenoids… zeaxanthine, lutein,
lycopene, etc
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STAGE TWO – PROMOTION
Cancer cells start to form a tumor
(often benign, often precancerous)
Natural growth factors stimulate growth of cancer cells
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Dangerous Growth Factors
• Insulin and insulin-like growth factors
(which structurally respond to sugar just like insulin)
• Wrong kinds of fats:
• Eicosanoids are hormone-like substances that control
cell growth. The bad eicosanoids stimulate the growth
of cancer cells.
They come from:
• Vegetable oils – omega 6 polyunsaturated fatty acids
(corn, safflower, sunflower, etc)
• Meat from animals fattened on corn
• Trans fats (from fried foods, crackers, chips)
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Consume the Good Fats –
Omega 3 Fatty Acids … Fish Oil
There are also GOOD eicosanoids… that inhibit cell
growth and come from eating Omega 3 fatty acids (fish oils).
• Omega 3s from vegetable oils are only 10%
converted to good eicosanoids.
• Eat fish sparingly ...
…Beware the toxins they contain.
• Fish oil supplements may be safer than eating fish.
• Shaklee Omega Guard
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Why Use Omega-3 Supplements?
Many salmon are contaminated with PCBs & heavy metals
Current EPA recommendations for frequency of consumption:
Type of salmon:
Wild Coho & pink
Most Wild Chinook & Sockeye
Eat no more than:
1X/week
1-2X/month
Wild Alaskan Chinook
1X/month
Farmed Wash. State or Chile
1X/month
Farmed Canada, Maine, Norway
1X every 2 months
Farmed Scotland &Faroe Islands
1X/year
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Omega 3 Fatty Acids…
Shaklee Omega Guard
• Ultra pure, pharmaceutical grade,
full spectrum of 7 Omega 3 fatty acids
• Reduces risk of heart disease and stroke
But that’s not all…
• Also improves eczema, colitis, arthritis, MS,
psoriasis, migraines, reduces Creactive protein,
• Important for brain, eyes, joints, helps ADD
& ADHD, memory loss and depression
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What to Eat
to Prevent Promotion Stage
• Low fat protein (grass fed meats & vegetable
proteins)
• Avoid fried foods
• Use olive oil-based salad dressings
• Use mono-unsaturated oils like canola & olive oil
• Stir fry with small amounts of peanut oil or grape
seed oil
• Limit farm-raised salmon consumption. They are fed
ground up fish which contains PCB’s. Salmon cannot
make Omega 3. That comes from plankton ( from
cold water ) which small fish eat and then salmon eat
them.
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• Beware discount store fish oil –contamination likely
More About Promotion
(Differentiation vs Cell growth)
Normally – we start as an
embryo with undifferentiated
cells that are dividing . These
develop differentiate into
specialized cells like brain,
skin & bone cells with limited
growth potential.
But with cancer.. Process is
reversed. Specific cells
become less differentiated
and acquire uncontrolled
growth potential. steve
Nutrients to Help Prevent
Promotion Stage of Cancer
• Natural nutrients slow cell division
• Carotenoids turn into Vitamin A
• Vitamin A and Vitamin D both
stimulate cell differentiation and
slow cell growth
(ex. keep bone cells as bone cells,
and skin cells as skin cells and
help prevent them from
becoming cancer cells )
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Stage 3 of Cancer -- Progression
• Tumors grow and spread.
• Now we must rely on our
immune systems to zap cancer
cells before the tumors grow
too large.
• Immune cells must destroy cells
in benign tumors before they
become malignant as well as
cancer cells that have already
formed
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What Do We Need to Halt Progression?
Antioxidants -- because immune cells use free
radicals to kill cancer cells ( and viruses, bacteria )
• The cells have to be protected from the free
radicals.
Immune cells contain phagosomes that engulf
the cancer cell and then create free radicals to
kill it.
B Vitamins and Protein are needed to produce
lots of immune cells because when the body is
under attack and the body needs to quickly
produce many immune cells.
Iron, zinc and trace minerals are required to
produce specialized proteins for the immune cells.
Probiotics (friendly bacteria ) are required
because 70-80% of the immune system is located in
the gut .
steve
Natural Sources for the nutrients to help
combat cancer
Antioxidants
• Vita E, C, carotenoids, flavonoids, polyphenols –
from vegetables, fruits
Other Important Nutrients
• B vitamins – from vegetables and fruits
• Protein – from vegetable proteins, poultry, fish
• Minerals – from whole grains
• Probiotic friendly bacteria – yogurt
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OR …
Supplements can supply these essential
nutrients in higher and more dependable levels
• Vitalizer
• Shaklee 180 / Energizing Soy
• Vivix
• And Nutriferon – helps keep the
immune system vigilant.
Your body produces new cancer cells every day
So you need your immune system to be on
the lookout for cancer cells every day of your life .
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NUTRIFERON
Powerful breakthrough in
immune system science
Naturally boosts interferon
production
Created by the Nobel Prize laureate
who discovered interferon
Every day our bodies produce cancer cells.
We need a strong immune system every day of
our life to protect us from them...
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Nutrients Essential for Immune
System to Zap Cancer Cells
• Vitamin C
• Vitamin E
• Carotenoids
• Flavonoids
Vitalizer
• B vitamins
• Iron
• Optiflora (friendly
bacteria)
• Energizing Soy Protein/ 180 Shakes & Bars
• Nutriferon
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Vitalizer – 80 Nutrients in Bio-Available Form
( that means .. You can absorb and utilize them)
Support Immune System with
Healthy Life Style Choices
• Minimize Stress
• Cortisol stimulates cancer cells to grow
• Stress Relief Complex/ B Complex
• Yoga/ meditation
o Inadequate diet
• Nutrients for a healthy immune system come from
vegetables, fruits, whole grains, fish & other healthy
protein sources.
• Immune nutrients are not found in sugar, carby snack
foods, many baked goods, soda pop ( they deplete them)
o Minimize toxins
o Use Shaklee Get Clean Products.. Good for your wallet and
your immune system.
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Final thoughts
• Cancer takes years to develop
• There are many things we can do
to reduce our risk.
• We can’t control genetics
• We can’t control all environmental factors
• So never blame yourself or what you did or did not
do.
Steve Chaney PhD Dr. Chaney holds a B.S. in Chemistry from Duke University and a Ph.D. in Biochemistry from
UCLA.
He is a retired professor in the Department of Biochemistry, Biophysics and the Department of Nutrition at the
University of North Carolina where he taught first year medical students as well as headed an active cancer research
program for 30 years.
Dr. Chaney has published over 95 papers in peer reviewed scientific journals, plus 12 reviews and two chapters on
nutrition for one of the leading biochemistry textbooks for medical students today. He’s also been named “Teacher of
the Year” several times by the first year medical students and currently holds a Medical Alumni Distinguished
Teaching Professorship. Steve and Suzanne are 30 year Master Coordinators with Shaklee.