Transcript HERPESVIRIDAE

PARVOVIRIDAE
PETER H. RUSSELL, BVSc,
PhD, FRCPath, MRCVS
Department of Pathology and
Infectious Diseases, The Royal
Veterinary College,
Royal College Street,
London NW1 OTU.
E-mail
Web site
LEARNING OBJECTIVES
Students should be able to:
• Relate the pathogenesis of feline infectious
enteritis virus to its control
• Explain the origins of canine parvovirus type
2 and its role in canine disease
• Describe the importance and control of
porcine parvovirus as a reproductive
pathogen
• List the species and disease conditions in
which papilloma viruses are implicated
FAMILY
CHARACTERISTICS
FELINE PARVOVIRUS
DISEASE AND PATHOGENESIS:
FELINE PARVOVIRUS
DIAGNOSIS:
FELINE PARVOVIRUS
HOST RANGE : All felidae; mustelidae
(mink) and some procyonidae (racoons and
panda).
FELINE PARVOVIRUS
ANTIGENICITY & CONTROL:
CANINE PARVOVIRUS
TYPE 2
CANINE PARVOVIRUS
TYPE 2
DISEASE AND PATHOGENESIS:
Infection via oropharyngeal route followed by
viraemia.
Initially, there were two distinct syndromes
associated with CPV-2: (1) targeted at rapidly
dividing myocardial cells, (2) at the rapidly
dividing cells in the crypt epithelium of the
small intestine.
CANINE PARVOVIRUS
TYPE 2
DIAGNOSIS:
CANINE PARVOVIRUS
TYPE 2
HOST RANGE Dogs (but CPV-2a & 2b
can cause disease in cats - see below)
CANINE PARVOVIRUS
TYPE 2
ANTIGENICITY & CONTROL:
PORCINE PARVOVIRUS
DISEASE AND PATHOGENESIS
PORCINE PARVOVIRUS
HOST RANGE: pigs
PORCINE PARVOVIRUS
EPIZOOTIOLOGY:
PORCINE PARVOVIRUS
ANTIGENICITY & CONTROL:
SUMMARY
• Cause serious diseases in cats (enteritis/
panleucopenia), dogs (myocarditis/
enteritis) and pigs (SMEDI).
• Pathogenesis is related to the requirement
for rapidly dividing cells for virus
replication
• Vaccines available for each disease which
prevent viraemia & hence destruction of
rapidly dividing cells.