Transcript Herpes genitalis & Syphilis

HERPES GENITALIS
& SYPHILIS
Mia Smoljan
Mentor: A. Žmegač Horvat
Herpes genitalis



STD caused by HSV
Remissions and relapses
Symptoms:



Diagnosis:



reddening of the skin with small, fluid-filled blisters
and ulcers
initial episodes may be more severe – inguinal
lymphadenopathy, fever, malaise, headache
PCR
Tzank test
Treatment: Acyclovir
http://www.youtube.com/watch?v=TY8XhAKI
7CI/





Herpes neonatalis
Dangerous complication that affects babies
born while mother has an active infection
during parturition
Symptoms appear between 1st and 2nd
week of life
Can affect:







skin
CNS
eye
mouth
liver
lungs
........
Prevention: Cesarean section
Treatment: Acyclovir
Syphilis



Chronic STI caused by Treponema pallidum
Acquired via direct sexual contact with the
infectious lesions of a person with syphilis
PRIMARY SYPHILIS: a few weeks after
infection
–
–
chancre/hard ulcer
after 4 to 6 weeks heals spontaneously

SECONDARY SYPHILIS:
–
–
–
–
–
1–6 months (commonly 6 to 8 weeks) after the
primary infection
symmetrical reddish-pink non-itchy rash on the
trunk and extremities
condylomata lata (rash becomes flat, broad,
whitish lesions)
most contagious stage!!
meningismus, enlarged lymph nodes, fever....

TERTIARY SYPHILIS:
–
–
1–10 years after the initial infection
formation of gummas =

–
–
–
–
–
soft, tumor-like balls of inflammation – granulomas
neuropathic joint disease
neurosyphilis
tabes dorsalis
cardiovascular syphilis – ascending aorta!!
cor bovinum


Diagnosis: serology (VDRL antibody test, TPHA)
Treatment:
 penicillin