Transcript Molecular Machines (Jacobson) Group

Molecular Machines (Jacobson) Group
red blood cell
~5 m (SEM)
DNA
proteins
nm
Simple
molecules
<1nm
diatom
30 m
bacteria
1 m
10-10
10-9
10-8
10-7
10-6
m
10-5
10-4
10-3
10-2
SOI transistor
width 0.12m
semiconductor
nanocrystal (CdSe)
Nanometer memory element
2nm
(Lieber)
1012 bits/cm2 (1Tbit/cm2)
Circuit design
Copper wiring
width 0.2m
IBM PowerPC 750TM
Microprocessor
7.56mm×8.799mm
6.35×106 transistors
Fabrication Figure of Merit
Ffab = ln (W) / [
3
a
tfab Efab ]
Fab in a Box
NanoTectonics
All Printed-All Inorganic 3D
nm Building Blocks – Seconds Per Layer
Nanocluster Building Blocks
TFT Devices
Liquid Processed Chips
Multilayer Liquid Assembly
Ridley et. Al, Science, 286, 746 (1999)
Molecular Machines (Jacobson) Group
Bulthaup et. Al. APL 79(10): 1525 (2001)
Molecular Machines
There is Plenty of Room at the Bottom, December 29th,
1959
What I want to talk about is the problem of manipulating and
controlling things on a small scale.
Richard P. Feynman
(1918-1988)
As soon as I mention this, people tell me about miniaturization,
and how far it has progressed today. They tell me about electric
motors that are the size of the nail on your small finger. And
there is a device on the market, they tell me, by which you can
write the Lord's Prayer on the head of a pin. But that's nothing;
that's the most primitive, halting step in the direction I intend to
discuss. It is a staggeringly small world that is below. In the
year 2000, when they look back at this age, they will wonder
why it was not until the year 1960 that anybody began
seriously to move in this direction…..
It is remarkable that given enough time, the
synthetic chemist can usually synthesize
what they set out to make.
http://www.zyvex.com/nanotech/feynman.html
Acc. Chem. Res., 30 (10), 393 -401, 1997. 10.1021/ar950199y S00014842(95)00199-3
Copyright © 1997 American Chemical Society
Synthetic Supramolecular Chemistry
Matthew C. T. Fyfe and J. Fraser Stoddart*
ATP Synthase
Molecular Architecture of the Rotary Motor in ATP Synthase
Daniela Stock, Andrew G. W. Leslie, and John E. Walker
Science Nov 26 1999: 1700-1705
BioMolecular Machines
Why They And Their Synthetic
Analogs Are The Next Revolution
- Bypass Moore’s Law: Extremum in Cost / Size / Yield
- Combinatorically Interchangeable Parts
- Self Replicating
Radio Frequency Control of
Biomolecular Machines
Molecular Machine (Jacobson/Hamad) Group
Center for Biomedical Engineering (Zhang)
MIT
Hamad-Schifferli Nature 415 (6868),
152 (2002)