Transcript Document

Cellular and Molecular Neurosciences
Investigate biophysical, molecular and cellular mechanisms of synaptic transmission and
plasticity under normal and pathological conditions-link between gene function and brain
disorders-crucial step in the development of novel efficient therapies.
Faculties: Yoav Gothilf, Ilana Lotan, Pablo Blinder, Nathan Dascal, Moshe Rehavi,
Uri Ashery, Izhak Michaelevski, Inna Slutsky, Ari Barzilai, Bernard Attali
Research Techniques: Electrophysiology, Slice recording, Total Internal Reflection
Fluorescence (TIRF), stochastic optical reconstruction microscopy (STORM), multiphoton imaging, Fluorescence Resonance Energy Transfer (FRET), Molecular genetics
and Biochemistry, Proteomics, Mass-Spectrometry, Model simulation,
Immunohistochemistry, MRI, Behavioral tests
Yoav Gothilf
The circadian clock system: underlying molecular mechanisms, functional
development and light entrainment. Hypothalamic control of sexual maturation
and reproduction. Zebrafish as a model to study Alzheimer's disease
Ilana Lotan
voltage-gated potassium (Kv) channels in transmitter and hormone release
Pablo Blinder
physiology and structure of the neurovascular interface under normal and pathological
conditions
Nathan Dascal
Molecular mechanisms of signal transduction by neurotransmitters in neurons,
and their relation to cell function and to human disease
Moshe Rehavi
molecular mechanisms of drugs for neuropsychiatric disorders
Uri Ashery
molecular mechanisms of synaptic transmission and plasticity under normal
conditions, during neurodegenerative diseases and in aging
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The synaptic vesicle cycle
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Izhak Michaelevski
Molecular and Functional Neurobiology of Mechanisms of the Episodic Memory
and its impairment
Inna Slutsky
Regulation of Hippocampal Plasticity: From Single Synapse Dynamics to
Alzheimer’s Disease
Ari Barzilai
Effects of mal-functioning DNA damage response on neuro-glio-vascular units in
brain diseases. Molecular mechanisms of optic nerve degeneration and
regeneration
Bernard Attali
Structure, biophysics and physiology of normal and diseased potassium channels
in the brain and heart
Epilepsy