Transcript CPS 302 Society, Science, and Technology

CPS 302 Society, Science,
and Technology
Wensheng Shen
Department of Computational Science
SUNY Brockport
The Nobel Prize
• What is Noble prize? Is it the most prestigious prize in
the world?
– Established in 1895. First prize in 1901.
– Physics, chemistry, physiology or medicine, literature, and
peace.
– It is conferred annually on December 10.
– Where is the award conferred?
– Later on, an associated prize on economics was added in 1968
by Sweden’s Central Bank and first awarded in 1969.
• Who is Alfred Nobel?
– 1833—1896
• What is his nationality?
World prize in mathematics
• Why there is not Nobel prize in Mathematics?
– Maybe he was not particularly interested in
mathematics or theoretical science.
• Fields medal
– Founded in the name of Canadian mathematician
John Charles Fields.
– The top honor to a mathematician.
– The receiver should be less than 40.
– It is awarded every 4 years.
2009 Nobel Prize Winners
• Physics:
– Charles K. Kao
• Standard Telecommunication Laboratories, Harlow, United
Kingdom;
• Chinese University of Hong Kong, Hong Kong, China
• For groundbreaking achievements concerning the
transmission of light in fibers for optical communication
• Copper wires
• Glass fibers
• Electromagnetic interference
– Willard S. Boyle and George E. Smith
• For the invention of an imaging semiconductor circuit --- the
CDD sensor
• CCD (charge-coupled device): convert light into electrons
• CCD sensor and CMOS (complementary metal oxide
semiconductor) sensor
• Chemistry:
– Venkatraman Ramakrishnan
• MRC Laboratory of Molecular Biology, Cambridge,
United Kingdom
– Thomas A. Steitz
• Yale University, New Haven, CT, USA
– Ada E. Yonath
• Weizmann Institute of Science, Rehovot, Israel
The ribosome translates the DNA code into life. Ribosomes produce proteins,
which in turn control the chemistry in all living organisms.
As ribosomes are crucial to life, they are also a major target for new antibiotics
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They have showed what the ribosome looks like and how it functions at the
atomic level. All three have used a method called X-ray crystallography to
map the position for each and every one of the hundreds of thousands of
atoms that make up the ribosome.
Inside every cell in all organisms, there are DNA molecules. They contain
the blueprints for how a human being, a plant or a bacterium, looks and
functions. But the DNA molecule is passive. If there was nothing else, there
would be no life.
The blueprints become transformed into living matter through the work of
ribosomes. Based upon the information in DNA, ribosomes make proteins:
oxygen-transporting haemoglobin, antibodies of the immune system,
hormones such as insulin, the collagen of the skin, or enzymes that break
down sugar. There are tens of thousands of proteins in the body and they all
have different forms and functions. They build and control life at the
chemical level.
An understanding of the ribosome's innermost workings is important for a
scientific understanding of life. This knowledge can be put to a practical and
immediate use; many of today's antibiotics cure various diseases by
blocking the function of bacterial ribosomes. Without functional ribosomes,
bacteria cannot survive. This is why ribosomes are such an important target
for new antibiotics.
This year's three Laureates have all generated 3D models that show how
different antibiotics bind to the ribosome. These models are now used by
scientists in order to develop new antibiotics, directly assisting the saving of
lives and decreasing humanity's suffering.
• Physiology or Medicine:
– Elizabeth H. Blackburn:
• Professor of biology and physiology at the University of
California, San Francisco
– Carol W. Greider:
• Professor in the department of molecular biology and
genetics at Johns Hopkins University School of Medicine in
Baltimore
– Jack W. Szostak:
• Professor of genetics at Massachusetts General Hospital in
Boston
They solved a major problem in biology: how the chromosomes can be
copied in a complete way during cell divisions and how they are
protected against degradation. The solution is to be found in the ends of
the chromosomes – the telomeres – and in an enzyme that forms
them – telomerase
Peace Prize
Barack H. Obama:
For his extraordinary efforts to strengthen
international diplomacy and cooperation
between people