Transcript Sickle Cell PPT

SICKLE CELL
BY:
LOGAN STARR, EVAN MCCRAY, MORGAN PRATT, ANGELA VILLEGAS
TYPE OF GENETIC DISORDER
• Sickle cell disease is caused by a mutation in the hemoglobin-beta gene found
on chromosome 11. Hemoglobin transports oxygen from the lungs to other
parts of the body. Red blood cells with normal hemoglobin (hemoglobin-A)
are smooth and round and glide through the blood cells.
•
Sickle cell disease is inherited. Two genes for the sickle cell hemoglobin must
be inherited from ones parents in order to have the disease. A person who
receives a gene for sickle cell disease from one parent and a normal gene
from the order has a condition called sickle cell trait.
CHROMOSOME GRAPHIC
SYMPTOMS OF DISORDER
•
•
•
•
•
Pain in joints
Sudden pain in chest
Dizziness
Blood in urine
Inflamed fingers and toes
* All of these symptoms are caused by damaged cells clumping together and sticking
to the walls of the blood vessels blocking blood flow to certain areas of the body.
EFFECTS OF DISORDER
THE EFFECTS ARE
- Lack of oxygen
- Anemia
- Hypoxemia
the cells aren’t in there regular circle shape so it causes the blood flow
to slowdown / if not it will stop and cause lack of oxygen.
DIAGNOSIS OF INDIVIDUAL WITH
DISORDER
Doctors can diagnose people with sickle cell by a blood test. This blood test is
done in newborn’s and in adults. In adults the blood is draw from a vein in there
arm in newborn’s it is drawn from a finger or heel.
AJ GREEN SICKLE CELL STORY
When AJ was born in 1992, there was lack of information about the newborn
sickle cell disease. They only told him that he was going to have a PKU shot.
After the PKU shot the doctor called with some result and found out that he had
a sickle cell disease. AJ had his first sickle cell disease crisis at 8 mouths.
TREATMENTS AVAILABLE TO
INDIVIDUAL WITH DISORDER
Bone marrow transplant offers the only potential care, but finding a downer is
difficult. The procedure has a risk of death.
CURRENT RESEARCH
We have been learning about sickle cell for the past decade or so and we now
know how to treat certain conditions and symptoms for sickle cell. People with
sickle cell are now living to be 40-50 years old or more.
2ND GRAPHIC RELATED TO THE DISORDER
• The 2nd graphic related to sickle cell disease is Thalassemia which is a blood
disorder involving less than normal amounts of oxygen carrying protein in the
body.
SUMMARY
My little brother had sickle cell when he was younger he didn’t let it affect him
to much socially but it did affect him physically. It looked like he was always out
of breath. When he had it was hard to play a game of tag with him for very
long. He didn’t let that show he just kept trying and fighting with it and it was
finally gone but it didn’t seem to affect him very much.
WEBSITES
www.mayoclinic.org/diseases-conditions/sickle-cell-anemia/basics/testsdiagnosis/con20019348
https://www.google.com/webhp?sourceid=chromeinstant&ion=l&espr=2&ie=utf=8#q
=what+type+of+genetic+disorder+is+sickle+cell
www.mayoclinic.org/diseases-conditions/sickle-cellanemia/basics/treatment/con20019348
https://www.google.com/webhp?sourceid=chromeinstant&ion=1&espv=UTF=8&q=how+to+sickle%3Be+cell+disease+inherited
https://www.google.com/webhp?sourceid=chrome-instant&ion=1&espv=28ie=UTF8#q+what+are+the+symptoms+of+sickle+cell+disease%5C
www.webmd.com/pain-management-sickle-cell-disease
MORE WEBSITES
• www.ststh.co.uk
• https://www.google.com/webhp?sourceid+chromeinstant&ion=1&espv=2&ie=UTF8#q=what+is+the+2nd+related+graphic+to+sickle+cell+disease
• http://www.cdc.gov/ncbddd/sicklecell/stories.html
• Interview speaker in science class