Transcript Innovations in Nutraceuticals and functional foods

Nutraceuticals
The Road Ahead
V. HARIHARAN
CEO & MANAGING DIRECTOR
PHYTOTECH EXTRACTS PVT. LTD.
BENGALURU
INDIA
Nutraceuticals
“Nutraceutical are
defined as “Any substance that
is food or part of food that provides Medical
and/or Health benefits including prevention and
treatment of disease”
Dr. Steve De Felice
“Foundation for innovation in Medicine -US in 1989”
Back to Nature
Back to the nature to back our future
Nutraceuticals
Wellness - Nutraceuticals
A healthy balance of the body & mind results in
a feeling of well-being
Tiredness & stress are common problems today
and Nutraceuticals address these
Nutraceuticals will help to be good always !
Good means wellness
Pharmaceuticals & Nutraceuticals
Pharma says “Cure first and follow diet
next”, the Nutraceuticals says “Follow diet
first and cure next”.
Switch lifestyle from “Eat & Act”
(independently) to “Eat well & Act well”
(Dependently) – Choose
Nutraceuticals is best for the country and
best for the world
Pharmaceuticals & Nutraceuticals
According to a report by Frost & Sullivan, Indian
Nutraceuticals market is projected to grow to US $4
billion in 2018 at a compound annual growth rate
(CAGR) of 17%
Functional foods & beverages constitute 60% of the
Indian Nutraceuticals market while rest 40% is
dietary supplements
Laws governing
DHSEA – Dietary Health Supplement & Education
Act (USA)
FSMA – Food Safety Modernisation Act 2011
FOSHU- Foods for Special Health Use (Japan)
FSSAI - Food Safety Standards Authority of India
Codex regulations are on the anvil
WHO is working on the guidelines for Nutraceuticals
Issues
Quality , Safety and
Efficacy
Standardization
Active compound isolation
Elaborate pharmacological
testing & toxicity testing
SAR ( Structure Activity
Relationship)
Issues
Use of marker compounds
Finger Printing
Use of sophisticated equipments – HPTLC
Stability Testing – Accelerated & Ambient temp
Expiry dates
INNOVATIONS
Product and Package
The innovations should take care of Newer
concepts built in to the product design focusing
stability and safety of the product
Product should be delicious and palatable
Product should be customer friendly with
convenience & compliance
Package should be with easy administration
Should be economical and affordable to common
man
Focus on R&D
Selecting right Nutraceutical dosage forms.
De-bitterizing the extracts and making palatable
formulations.
Deeper insight of In-vitro & in-Vivo studies of the
actives as well as the formulations
Conducting stability studies following ICH guidelines
and conforming the shelf life of the products
Trade dress with consumer friendly packaging
Conforming to FSSAI regulations
Newer Products
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Switch over from conventional dosage forms
such as tablets, capsule and liquids to newer
innovative forms :
Herbal Teas
Instant Energy bars
Ready to Drinks ( RTDs)
Chocolates / Candies
Gummies ( Gelatin ,Pectin or Fruit base )
Newer products ..
• Chewing gums
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Chewable capsules
Lozenges
Pastilles
Buccal Films
Sublingual drops
Instant dissolving granules
Biscuits, Cookies and Diskettes
Popsicles and so on…
Aloe & Collagen Drink
Buccal Films
NUTRIGENOMICS
Addresses the role
of diet in gene
expression
Nutrigenomics – Future
Development of
personalized foods for
the future
The DNA diet (Should
your genes decide what
you like to eat?)
Nutrigenomics – Future
Scientists have identified a
few novel Bcl-2
phosphorylating molecules
and Cox-II inhibitors from
herbal products and
functional foods and they are
in the process of developing
new food products by placing
them in the foods
Nutrigenomics – Future
e.g.: CoxII cereals (adding Cox II
inhibiting nutraceuticals in cereals),
CoxII cookies, CoxII juices, CoxII
chocolates, Bcl-2 chocolates,
candies, cookies, muffins and soft
drinks (anti-Bcl-2 Nutraceuticals).
Finally, with the presence of more
new nutraceuticals in the pipeline
than ever before, the juncture
between discovery and the effect on
genes and proteins is underway
Formulations
All parts of our body age but you know the
tongue never ages. So the taste is the most
important for a Nutraceutical product
Ahara (Food)
Anna (Nutrients )
Food prepared with love & affection (care) give
more nutrients . So too, are the Nutraceutical
formulations
THANK YOU