Transcript pptx
Challenges to the Modern Synthesis
Stephen Jay Gould, 1941-2002
Nils Eldredge, 1941-2002
DNA
Transcription
Translation
Notion of “gene expression”
Question: Why aren’t “identical twins” identical?
Epigenetics
From Wikipedia:
“Epigenetics is the study of heritable changes in gene
expression or cellular phenotype caused by mechanisms other
than changes in the underlying DNA sequence.”
http://www.pbs.org/wgbh/nova/body/epigenetics.html
Is epigenetics why cloned animals don’t fare well?
Genetic regulation
Genetic Switches (in “non-expressed” regions)
Genetic Regulatory Networks
Random Boolean Networks
as models of genetic regulatory networks