Transcript Nutritional support for - Park County Chiropractic

The Immune and Enteric
Systems
Sue Howell, DVM
The Immune System
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www.nobelprize.org
Identify potentially injurious substances
Distinguish self from non-self
Assess level of threat
Mount an appropriate response
Repair damage
Inflammation
• Body’s natural
response to insult
• Vital to survival
• Meant to be turned
on for a short time
Ingredients that support the
immune system
• Spanish black
radish
• RNA
• Buckwheat leaf
juice and seed
• L-glutamine
http://vimeo.com/62369403
Adaptogens
Ginseng
(Eleutherococcus senticosus )
Ashwaganda
(Withania somnifera )
Canine Immune Support
Feline Immune Support
Indications
• General immune system support
• Colder climates or during the
fall/winter months
• When kenneled or in a shelter
Star
Star
History
• 6 year old F/S DSH
• Chronic URI resolved with doxycycline,
hyperglobulinemia with polyclonal gammopathy diagnosed
1 year prior
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No follow up viral panel. No viral testing
Presentation
• Severe crusting and ulceration of the ears, face, and
forelimbs
• Lesions bleed easily when touched
• Splenomegaly
• Lethargy
Star
Diagnostics
• Negative skin scraping, 3+ cocci on skin cytology, woods
light negative
• FIV positive
• Hyperglobulinemia
• Lymphopenia
Recommendation
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Clavamox
Itraconazole pending fungal culture
Nutritional support for the immune system
Grain-free canned diet
Star
Recheck (2 weeks)
• Lesions were drying up and 50% resolved
• More active
• Fungal culture negative
Recommendation
• Continue Clavamox
• Continue nutritional support for the immune
system
Star
Recheck (4 weeks)
• Skin lesions resolved
• Spleen smaller and less nodular upon palpation
Recommendation
• Continue nutritional support for the immune
system
Recheck (6 weeks)
• No lesions
• Active and glossy hair coat
• Spleen unchanged
• Owner is thrilled!
The Gastrointestinal System
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70% of immune system
Enterocytes
Mucosal barrier
Gut flora
Enteric nervous system
Leaky Gut Syndrome
Source: www.ktcolgan.com
Gut Flora
• detoxifies some
xenobiotics
• maintains the intraluminal
environment
• dialogues with the
immune tissues of the gut
• stimulates bone marrow
Biomedical Imaging Unit, Southampton General Hospital
Behavior
Enteric Support Ingredients
Canine Enteric Support
Feline Enteric Support
Systems Supported
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Digestive system
Liver
Kidneys
Immune system
Endocrine system
Canine Enteric Support
Feline Enteric Support
Indications
• General enteric support
• Patients with increased metabolic
demand
• Hepatic patients in need of
additional enteric support as
indicated by ALT, alkaline
phosphatase, bile acids studies,
and enteric histopathology
• Patients with immune challenges
Lexi
History
• Pancreatitis 2 years ago
• “Sensitive stomach” and
infrequent soft stool
• 11/27/13 – diarrhea and one
episode of vomiting, suspected
URI
• 12/3/13 – suspected pneumonia
• 12/31/13 – OSU consult
• 1/1/14 – whipworms diagnosed
Lexi
Diagnosis
Lymphangectasia with
concomminent mild
IBD
Lexi
Medications
• Azothioprine, Tylan powder, low
dose aspirin, Prednisone, Vit B12
Nutritional support for
• the immune system
• the gastrointestinal system
• essential amino acids
Progress
• 2/4/14 normal protein levels,
weaning off medications,
continue nutritional support