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Chapter 3:
Biochemistry
Honors Biology 2011
What
are we
made of?
Why
do we
have to eat?
Elements of Life
96% of living
organisms is
made of:
carbon (C)
oxygen (O)
hydrogen (H)
nitrogen (N)
The Chemistry of Carbon
Living organisms are made of carbon based molecules
known as organic molecules.
Carbon’s versatility is the key to the structure of organic
molecules:
Carbon can bond with up to 4 other atoms at once.
Carbon can form single, double or triple bonds.
Carbon bonds easily with other carbon atoms to form the
backbone of large organic molecules.
Carbon can bond with many different
elements such as H, O, P, S, N.
Macromolecules
Most molecules in cells are so large they
are macromolecules or “giant molecules”
made from thousands
of smaller molecules
Polymerization: large molecules
are made from joining smaller
ones together
Monomers:
small building blocks
Polymers: long chains of monomers
Building large molecules of life
Chain together smaller molecules
building
block molecules = monomers
Big molecules built from little molecules
polymers
Building large organic molecules
Small molecules = building blocks = monomers
Bond them together = polymers
Making Polymers
Monomers link to form
polymers in a reaction
called a condensation
reaction
One small molecule
comes out each time
two monomers
form a bond.
When that molecule is water, it’s called dehydration
synthesis.
Monomer + Monomer Polymer + Water
Example of synthesis
amino acids
protein
Proteins are synthesized by bonding amino acids
amino acids = building block
protein = polymer
How to take large molecules apart
Digestion
Hydrolysis
taking
big molecules apart
getting raw materials
for synthesis & growth
making
energy (ATP)
for synthesis, growth & everyday functions
+
Energy
Breaking Down Polymers
Polymers can be broken
down back into monomers
by a reaction called
hydrolysis.
Water is added to break a
bond between monomers.
Exergonic reaction
(energy comes out)
Polymer + Water Monomer + Monomer
Example of digestion
Energy
Energy
Energy
Energy
Energy
starch
Energy
glucose
Energy
Starch is digested to glucose
Energy Currency
Life processes require energy
Adenosine Triphosphate (ATP) is a
molecule that contains LOTS of energy
When P is removed,
energy is released
and can be used by
the cell.
Section 3-3:
Molecules of Life
Molecules of Life
Put C, H, O, N together in different
ways to build living organisms
What are bodies made of?
carbohydrates
sugars & starches
proteins
fats
(lipids)
nucleic acids
DNA, RNA
Why do we eat?
We eat to take in more of these chemicals
Food
for building materials
to make more of us (cells)
for growth
for repair
Food
to extract energy
Unit = calorie
to make ATP
ATP
What do we need to eat?
Foods to give you more building blocks
& more energy
for building & running bodies
carbohydrates
proteins
fats
nucleic
acids
vitamins
minerals, salts
water
Don’t forget water
Water
65%
of your body is H2O
water is inorganic
doesn’t contain carbon
Rest of you is made of carbon molecules
organic
molecules
carbohydrates
proteins
fats
nucleic acids
Carbohydrates
Elements: C, H, O
in a 1:2:1 ratio
Monomer = Building block molecules =
monosaccharide
or simple sugar (glucose, fructose, galactose)
sugar sugar sugar sugar sugar sugar sugar sugar
sugar - sugar - sugar - sugar - sugar
Carbohydrates
Function:
quick
energy
energy
glucose
C6H12O6
storage
structure
cell wall in plants
sucrose
Examples
sugars
starches
cellulose
(cell wall)
starch
Monosaccharides = Sugars = building blocks
Names for sugars usually end in -ose
CH2OH
glucose
fructose
sucrose
maltose
H
O
H
OH
H
H
OH
HO
H
OH
glucose
C6H12O6
sucrose
fructose
maltose
Building carbohydrates
Disaccharides = 2 monosaccharides put together by
dehydration synthesis.
Example: Maltose = glucose + glucose
monosaccharides
|
glucose
|
glucose
2 sugars =
disaccharide
|
maltose
Building carbohydrates
Dehydration Synthesis
monosaccharides
|
glucose
|
fructose
2 sugars =
disaccharide
|
sucrose
(table sugar)
BIG carbohydrates
Polysaccharides
starch
energy storage in plants
potatoes
glycogen
energy storage in animals
in liver & muscles
cellulose
structure in plants
cell walls
chitin
structure in arthropods & fungi
exoskeleton
Cellulose
Cell walls in plants
herbivores can digest cellulose well
Cross-linking between polysaccharide chains hard to digest,
most carnivores cannot digest cellulose
that’s why they
eat meat
to get their energy
& nutrients
cellulose = roughage
stays undigested
keeps material
moving in your
intestines
Lipids
Concentrated energy
molecules
Elements: C, H, O
Lipids are not polymers- only made of 4 parts, not a
long repeating chain
Made of Glycerol & Fatty Acids (long, unbranched carbon
chains)
Lipids are large,
nonpolar organic
molecules that do
not dissolve in water.
Lipids
Function:
energy
storage
very concentrated
twice the energy as carbohydrates!
cell
membrane
cushions organs
waterproofing
insulates body
think whale blubber!
some
hormones
Lipids
Examples
fats
oils
waxes
hormones
sex hormones
testosterone (male)
estrogen (female)
Molecular Structure of Fat
not a chain (polymer) = just a “big fat molecule”
Many C-H bonds that store more energy
than the C-O bonds common in other
organic compounds.
Saturated fats
Each carbon atom is
covalently bonded to four
atoms.
They are full or
saturated.
Contain LOTS of energy
Most animal fats
solid
at room
temperature
Limit the amount in your
diet
contributes
to heart
disease
deposits in arteries
Unsaturated fats
Carbon atoms that are not
bonded to the maximum
number of atoms that they
can bond to, form double bonds
and are said to be
unsaturated, not full.
Contain less energy than
saturated fats.
Plant, vegetable & fish fats
liquid
at room
temperature
the fat molecules
don’t stack tightly
together
Better choice in your
diet
Other lipids in biology
Cell membranes are made out of lipids
phospholipids
forms
a barrier
between the cell
& the outside
Other Types of Lipids
Wax - long fatty acid
joined to long alcohol chain.
Waterproof, form a protective coating on outer surfaces.
Steroids - four fused carbon
rings with various functional groups
attached.
Many animal hormones are steroids
Cholesterol is needed by the body for
nerve cells and other cells to
function normally.
Other lipids in biology
Cholesterol
good
molecule in cell membranes
make hormones from it
including sex hormones
but
too much cholesterol in blood may lead to
heart disease