Transcript Organic Chemistry Presentation

Organic Chemistry
Faculty Research Interests
Prof. Deb Dillner
Overview:
NMR Spectroscopy and Collaboration with
Professor Rehill (biology) on a project to
isolate and identify tannins from oak leaves.
Continuing projects:
1. Isolation and identification of tannins from
Oak leaves (Midn. J. Mohamed) – Combines
chromatography and NMR spectroscopy.
Prof. Deb Dillner
Overview:
NMR Spectroscopy and Collaboration with Professor
Rehill (biology) on a project to isolate and identify
tannins from oak leaves.
Continuing projects:
2.
Using NMR spectroscopy and Computational
Modeling to Investigate Conformation and Chemical
Shifts for Bicyclic Compounds.
2
H2
H3
Prof. Jeff Fitzgerald
Overview:
Synthesis and understanding of nonlinear optical
materials.
Continuing projects: Tetraazaporphyrin /
phthalocyanine hybrids for optical limiting.
- Optical limiters are materials which transmit
ambient light but are opaque to laser light.
- Some Pb phthalocyanine complexes show good
limiting but the analogous tetraazaporphyrin
complexes are disappointing.
Prof. Jeff Fitzgerald
Overview:
Synthesis and understanding of nonlinear optical
materials.
Continuing projects: Tetraazaporphyrin /
phthalocyanine hybrids for optical limiting.
- Optical limiters are materials which transmit
ambient light but are opaque to laser light.
- Some Pb phthalocyanine complexes show good
limiting but the analogous tetraazaporphyrin
complexes are disappointing.
Prof. Jeff Fitzgerald
Overview:
Synthesis and understanding of nonlinear optical
materials.
Continuing projects: Tetraazaporphyrin /
phthalocyanine hybrids for optical limiting.
- Optical limiters are materials which transmit
ambient light but are opaque to laser light.
- Some Pb phthalocyanine complexes show good
limiting but the analogous tetraazaporphyrin
complexes are disappointing.
- Alex Kriegel, ‘12, found a way to make and separate four hybrids of
phthalocyanine and tetraazaporphyrins.
N
N
N
N
N
Bz3TAP
N
N
N
Mg
N
N
N
N
N
N
N
N
Mg
N
N
N
N
N
N
N
N
N
Mg
N
N
Mg
N
N
N
N
N
cis-Bz2TAP
trans-Bz2TAP
BzTAP
- I would like to study the optical limiting behavior of Alex’s hybrids in
order to understand the structure required for effective optical limiting.
Assoc. Prof. Shirley Lin
Overview:
My background is in organometallic and supramolecular chemistry
with a focus on polymers.
My research interests are:
A) developing new catalytic transformations (with Prof MacArthur
and CDR Brown, USNA)
B) synthesis of new functional materials
C) chemical education (with Prof. Hartman, USNA)
Project : tandem catalytic synthetic methodologies (fulfills biochemistry concentration)
Hydrodehalogenation of ArCl and ArBr
Cyanation of ArCl
K. A. Cannon, M. E. Geuther, C. K. Kelly, S. Lin, and A. H. R. MacArthur Organometallics 2011 30 (15), 4067-4073
M. M. Coughlin, C. K. Kelly, S. Lin, and A. H. R. MacArthur Organometallics 2013 32(12), 3537-3543
Prof. Joe Urban
Overview:
Computational chemistry/molecular modeling of
organic and bioorganic compounds
Projects:
Molecular Modeling Studies of Model Peptide
Mimics
Computational chemistry techniques are being used
to investigate the conformational properties of
modified peptide compounds. The work involves
using molecular modeling software (ex: Spartan) on
local computers as well as remote DoD
supercomputers.
Current students: 1/C Mac Hastings
I am taking new research students. Please contact
me if you are interested. ([email protected])
Peptide Mimics by Modification of Peptides
Peptide Bond Modifications
R2
O
H
N
N
H
R1
peptide
R1
mimic
R2
R1
O
O
O
R1
H
N
N
H
O
peptide
R1
N
H
mimic
F
H
N
O
H
N
R1
O
mimic
CF 3 R2
H
N
O
O
H
N
mimic
CF 3 R2
H
N
F
H
N
Amino Acid Modifications
O
R1
H
N
O
mimic
• The mimics we study come from the modification of either the peptide
bond that links amino acids in a natural peptide, or the amino acids
themselves.
• We use molecular modeling to investigate how these modifications
impact the structure and properties of the mimics in comparison to their
natural peptide counterparts.
Professor Craig Whitaker
Overview:
My research areas focus on materials and
polymer chemistry.
Project:
Smart hydrogels incorporating chemical
agent markers and dye sensor molecules
are being synthesized and characterized.
The novel polymeric materials will use a
chemical reaction to detect and destroy
organophosphorus nerve agents (Sarin
gas). The stimuli-responsive hydrogels will
act as sensors when immersed in water
supplies, used as filtering materials or as
boundary layers in surgical masks.
Current students:
Ashley Gilliard (‘14), Allison Reitmayer (‘14)
and Elaine Zhong (‘14)