Transcript Global HIV/AIDS Implementation

Managing Procurement and
Logistics of HIV/AIDS Drugs
and Related Supplies
Introduction and Overview
May 30 to June 4, 2005
Abuja, Nigeria
Priority Setting and
Effectiveness
•
Prioritizing Programs of Care for People
with HIV/AIDS
•
Potential Priority Populations for the
Distribution of Antiretroviral Drugs
•
Avoiding the Pitfalls: Ways to Reduce
Costs and Improve Effectiveness of HIV
Control Programs
2
Intellectual Property Rights
• IPR: What are they?
• National Regulatory Situation – TRIPS
compliant flexibilities for different
countries (e.g., LDCs Developing)
• Specific provisions affecting developing
country members of WTO providing
public health flexibilities (e.g,
compulsory licensing, government use)
3
Financing and Pricing
What determines drug prices?
• Market segmentation,
differential and equity
pricing
• Additional price
determinants in retail
markets
• How can public purchasers
bargain for low prices
4
Pharmaceutical Systems Managing the Supply Side
• Who does what?
 What tasks need to be done?
 Who is already carrying out these tasks?
 Who can help in selection and quantification?
 Who can help with regulatory issues,
registration, IPRs and import?
 Who can help with procurement, storage and
distribution?
5
Product Selection & Quantification
Areas of Treatment
• Highly Active Antiretroviral Therapy (HAART)
for adults and adolescents
• Treatment of opportunistic infections
• Treatment of HIV infection in women of
childbearing potential, or pregnant women
• Treatment of HIV in children
• Prevention of Mother-to-Child transmission
• Post-exposure prophylaxis
6
Product Selection & Quantification
Essential Medicines for ARV
Treatment
• WHO publishes the authoritative list of
essential medicines for HIV/AIDS, including a
list of antiretrovirals (ARVs)
• Medicines should be selected by a
multidisciplinary team
• Consult www.who.int on a regular basis
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Product Selection & Quantification
What quantities of drugs need to be bought?
There are several options available to order
optimal quantities:
• Track usage
• Track usage and adjust the data for other
sites
• Estimate number of patient using the drugs
and disease data
8
Quality Assurance
• To introduce non-experts to
pharmaceutical quality control and
regulation
• Drugs must be safe, effective and of
consistent quality
• Adherence to GMP and compliance with
quality specifications are key
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Procurement
•
•
•
•
•
•
Assessing capacity
Commodities that support the HIV/AIDS
program
Planning procurement
Registering products
Choosing procurement methods
Pooled procurement (national or
regional)
10
Supply Chain Management

Storage

Inventory Control

LMIS
11
Rational Drug Use
Impact of RDU on other parts of
the pharmaceutical system
 Drug use as a management
function
 Factors influencing rational drug
use
 Irrational use of drugs

12
The Training Program
How is the Training Program organized?
Training Modules
•
Summary
•
Background
•
Case Studies
•
Instructor and Participant Versions
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