Transcript Norka Ruiz Bravo

Science for Global Health:
Fostering International Collaboration
IANAS Science Funding Workshop
26-28 July 2009
Norka Ruiz Bravo,PhD
Special Advisor to the Director
National Institutes of Health
U.S. Department of Health and Human Services
Outline
•Global Burden of Disease
•Biomedical Research Portfolio
•NIH Structure, Function
•Fogarty International Center
Global Burden of Disease,
Reported Mortality by Cause, 2004
World
Pop. ~ 6 billion
Region of the Americas
Pop. ~ 874 million
10%
10%
14%
31%
59%
76%
Communicable, Maternal, Perinatal, and Nutritional Conditions
Non-Communicable Diseases
Injuries
Source: World Health Report, 2008; Disease Control Priorities Project, 2006
Global Burden of Disease, Reported Mortality by
Cause, Non-Communicable Diseases,
Region of the Americas, 2004
7%
Malignant neoplasms
6%
25%
5%
6%
Cardiovascular
diseases
Respiratory diseases
Digestive diseases
Diabetes mellitus
8%
Neuropsychiatric
conditions
Other
43%
Source: World Health Report, 2008; Disease Control Priorities Project, 2006
Balanced National Biomedical Research Portfolio
Clinical
Research
Translational
Research
Basic Research
NIH - $30 B
Clinical Research
Translational
Research
Basic
Research
Private Sector - $60B
NIH Extramural Grants (FY 2008)
•Supports > 150,000 PIs & Key
Personnel
•About 83% of NIH budget
•Awards issued to > 3,000
institutions in > 100 countries
•Clinical, Basic, &
Translational Research
National Institutes of Health,
Bethesda, Maryland, Research Campus
National Institutes of Health:
The Steward of Biomedical and Behavioral
Research for the Nation
MISSION
Science in pursuit of fundamental knowledge about the
nature and behavior of living systems and the application
of that knowledge to extend healthy life and reduce the
burdens of illness and disability.
METHODS
 Supporting peer-reviewed scientific research at
universities, medical schools, hospitals, and research
institutions throughout United States and overseas
 Conducting research in its own laboratories
 Training research investigators
 Developing and disseminating credible health
information based on scientific discovery
Elias Zerhouni, M.D.
DirectorNIH
Director,
National
National Institute
Institute
on
on Aging
Aging
National
National Institute
Institute
on
on Alcohol
Alcohol Abuse
Abuse
and
and Alcoholism
Alcoholism
National
National Institute
Institute
of
of Allergy
Allergy and
and
Infectious
Infectious Diseases
Diseases
National
National Institute
Institute
of
of Arthritis
Arthritis and
and
Musculoskeletal
Musculoskeletal
and
and Skin
Skin Diseases
Diseases
National
National Cancer
Cancer
Institute
Institute
National
National Institute
Institute
of
of Child
Child Health
Health
and
and Human
Human
Development
Development
National
National Institute
Institute on
on
Deafness
Deafness and
and Other
Other
Communication
Communication
Disorders
Disorders
National
National Institute
Institute
of
of Dental
Dental and
and
Craniofacial
Craniofacial
Research
Research
National
National Institute
Institute
of
of Diabetes
Diabetes and
and
Digestive
Digestive and
and
Kidney
Kidney Diseases
Diseases
National
National Institute
Institute
on
on Drug
Drug Abuse
Abuse
National
National Institute
Institute
of
of Environmental
Environmental
Health
Health Sciences
Sciences
National
National Eye
Eye
Institute
Institute
National
National Institute
Institute
of
of General
General
Medical
Medical Sciences
Sciences
National
National Heart,
Heart,
Lung,
Lung, and
and Blood
Blood
Institute
Institute
National
National Human
Human
Genome
Genome Research
Research
Institute
Institute
National
National Institute
Institute
of
of Mental
Mental Health
Health
National
National Institute
Institute
of
of Neurological
Neurological
Disorders
Disorders and
and
Stroke
Stroke
National
National Institute
Institute
of
of Nursing
Nursing Research
Research
National
National Institute
Institute of
of
Biomedical
Biomedical Imaging
Imaging
and
and Bioengineering
Bioengineering
National
National Center
Center
for
for Complementary
Complementary
and
and Alternative
Alternative
Medicine
Medicine
Fogarty
Fogarty
International
International
Center
Center
National
National Center
Center
for
for Research
Research
Resources
Resources
National
National Library
Library
of
of Medicine
Medicine
National
National Center
Center on
on
Minority
Minority Health
Health and
and
Health
Health Disparities
Disparities
Clinical
Clinical Center
Center
Center
Center for
for
Information
Information
Technology
Technology
= Institutes and Centers that award grants
Center
Center for
for
Scientific
Scientific Review
Review
NIH Budget
Total FY 2009 Budget: $30.4 Billion
$4.7
84% Outside NIH
> 3,000 Organizations Worldwide
16% Inside NIH
$2.9 B Intramural Research (10%)
$1.2 B Staff & Buildings (4%)
$0.6 B Other (2%)
Spending at NIH
Spending Outside
$24.7
NIH – Extramural and Other Grant Awards, by Type
•
•
•
•
•
•
•
•
•
Research Grant Programs
New Investigators Program
Multiple Principal Investigators
Research Supplement Programs
Ruth L. Kirschstein
National Research Service Awards (NRSA)
Research Ethics and Training Grant Programs
NIH Career Development (K) Awards
Small Business Awards
Other Programs
Source: http://grants2.nih.gov/grants/funding/funding_program.htm
Mission
• Address global health challenges through
innovative and collaborative research and training
programs
• Support and advance the NIH mission through
international partnerships
• “Science for Global Health”
• FY 2009 Appropriation $68.7 million
Research and Research Training
~$50 million in grant awards
• 1/3 Research, 2/3 Research Training
• Awards range $10,000 - $1 million
• Low and Middle Income Countries
• Research Capacity Development and
Sustainability
Extramural Research Grants – 8 Programs
Fogarty International Research Collaboration Award (FIRCA)
International Cooperative Biodiversity Groups (ICBG)
Ecology of Infectious Diseases (EID)
International Studies on Health and Economic Development (ISHED)
Int’l Tobacco and Health Research and Capacity Building Program
Global Research Initiative Program for New Foreign Investigators (GRIP)
Stigma and Global Health Research Program
Brain Disorders in the Developing World: Research Across the Lifespan
Extramural Training Grants – 14 Programs
Fogarty International Collaborative Trauma
and Injury Research Training
Global Infectious Diseases Research
Training
International Clinical, Operational, and Health
Services Research Training Awards for
HIV/AIDS and Tuberculosis
International Research Ethics Education
and Career Development
International Maternal and Child Health
Research Training
Fogarty International Clinical Scholars Research
Training
International Centers for Excellence in
Clinical Research and Management Training
International Training Program in
Environmental and Occupational Health
Informatics Training for Global Health
Global Research Training in Population
Health
International Collaborative Genetics Research
Training
AIDS International Training and Research
International Clinical, Operational, and Health
Services Research Training Awards for Malaria
Framework Programs for Global Health
International Clinical, Operational, and Health
Services Research Training Awards (ICOHRTA) Chronic
Diseases: Goals and Objectives
Bridge the training gap for clinical, operational and health services research in
order to:
 Strengthen capacity to conduct clinical, operational, and health services
research to measure incidence and prevalence of non-communicable disorders
and diseases; characterize disease burdens; and devise, evaluate and
implement practical and affordable therapeutic or preventive interventions;
 Help LMICs apply current knowledge and new discoveries to clinical and
public health practice; and
 Support programs at research institutions to both train researchers and to
communicate and disseminate knowledge in support of evidence-based
policies.
 $2.5 million awarded to 12 institutions ($150k each in new awards and
$200k each in competing renewals) under previous PA issued in FY 2006
 New Program Announcement anticipated
 IC Partners: NCCAM, NIA, NIDA, NIDCR, NIMH, NINDS and OD/OD/Office of
Dietary Supplements
ICOHRTA Chronic Diseases:
Current Foreign Research and Training Sites
Poland
Czech Republic
Ukraine
Turkey
China
India Bangladesh
Thailand
Vietnam
Peru
Brazil
Argentina
ICOHRTA Chronic: Current Research
Training Areas
•
•
•
•
•
•
•
•
•
Evidence-based health care
Maternal & child health and nutrition
Suicide prevention and mental health
Nutrition-related chronic disease prevention
Finances and mental health
Smoking cessation and substance abuse
Oral health
Mental health, developmental disabilities and behavioral disorders
Community-based interventions to prevent drug use and HIV
transmission
Source: http://www.fic.nih.gov/programs/training_grants/icohrta/index.htm
Thank you for your attention!