Transcript DC_OpenTox_Intro

Douglas Connect
Introduction & background
5 September 2008
OpenTox Kick-off Meeting
Basel, Switzerland
[email protected]
[email protected]
These slides and their contents are Copyright © 2008 Douglas Connect. All rights reserved
Where we’re coming from…
• Our activities are all based on the foundations
of a community approach…
• …because we believe strongly in the concept
of the virtual organisation…
• …to achieve results in solving important
issues in education, research and healthcare…
• …and hence we are passionate about our
coordination role in OpenTox and working
towards establishing a world-leading
predictive toxicology platform.
Network & Community Projects
InnovationWell (innovationwell.net) is a member-based network of experts,
researchers and executives with a common interest in innovation and knowledge
management in the healthcare sector. The Community’s program has the goal of
achieving improved outcomes in healthcare product development & delivery through
cross-disciplinary use of innovative technologies, knowledge-based strategies and
supporting integrated and semantic-based informatics systems. (Founded end of 2003)
The eCheminfo Network and Community of Practice (echeminfo.com) is dedicated to
the communication of research and development of best practices in cheminformatics,
bioinformatics and modelling of relevance to drug discovery. The network involves a
diversity of subject matter expertise including experienced professionals from the life
science and pharmaceutical industry, vendors, research institutes, universities and
government. A number of recent international conferences and workshops have been
organised which have taken place in the UK, Switzerland and the USA, in addition to
several virtual conferences. (Founded end of 2003)
Development of our Networks
1. Networks with Community of Practice
Activity – learning, shared understanding Social network development (Start – 2003)
2. Addition of Community of Research Activity
– Collaborative research (Starting – 2008)
3. Motivate Addition of Community of
Innovation Activity – Value creation (2010 – )
eCheminfo Drug Discovery Workshop
Next Workshop; Hyderabad 15-18 December 2008
Best Practice Community Approaches
Initiation of Virtual Screening
Best Practice Initiative
Initiation of Virtual Screening
Best Practice Initiative – wiki-supported
SYNERGY Vision
Knowledge-oriented Collaboration
SYNERGY In Collaboration
Participate
EC FP7 funded
project commenced
1 February 2008.
Douglas Connect‘s
role: Industry Needs,
Assessment,
Requirements, Use
Cases, Piloting,
Validation.
Collaborate
Contribute
Pharmaceutical industry – Currrent Journey from
10,000 leads to 1 or 0 products on market
Progressing the development of safer more successful drugs
with collaboration approach. OpenTox Integrating Predictive
Toxicology Framework can help establish earlier prediction of
safety issues during discovery and development.
Knowledge Café Approach for OpenTox Kick-off Meeting in Basel
Primary Objectives of café discussions: build relationships, exchange knowledge, develop workplans
Form equal groups at café tables,
each with own topic.
Topic 1
Topic 2
Moderator facilitates discussion on table
specialty (topic). Wiki-supported at each
table for Knowledge capture
Rotate (disperse) members
based on their topic preferences,
Moderator stays fixed.
Topic 3
Topic 4
A sort of ‘musical chairs’.
Repeat until all members visit planned
number of table topics.
Topic 5