Transcript Sedatives - The SC EBS

Sedatives
Sedatives- Uses
Uses:
Preanesthetic
Antiepileptic
Anxiolytic
Treat insomnia
Muscle relaxation
Sedatives - Actions
Action:
Enhances GABA
Effects on
acetylcholine and
dopamine
Calming effects
Decrease anxiety
Side effects
Drowsiness, confusion
Depress respiratory
system
Synergistic effects
w/alcohol
GI problems
Dependence
Sedatives - Categories
Barbituates - Schedule II, III & IV
great risk of O.D. - toxic amount 10 times
recommended dose
(Phenobarbital)
(Pentobarbital)
Sedatives - Categories
Benzodiazepines - Schedule IV
less risk of O.D.
Valium (Diazepam)
anxiety, muscle relaxation
Side effects - drowsiness, fatigue, ataxia
Xanax (Alprazolam)
panic attacks, anxiety
less “buzz” effect than Valium
Benzodiazepines - Hypnotics
Halcion (Triazolam)
treat insomnia
side effects - “hangover feeling”, headache,
nausea, blurred vision, memory loss
was taken off the market for a while
Restoril (Temazepam)
“hangover feeling”
Dalmane (Flurazepam)
Treatment of sleeplessness
Legitimate uses of sleeping meds.
Other ways to treat insomnia
OTC sleeping meds. - take >20 min. to work
Diphenhydramine
Side effect - drowsiness
Sedatives
Very addicting
Very dangerous to quit
“cold turkey”
Withdrawal
Symptoms
Physical tremors, shakes,
headache, insomnia,
convulsions
Psychological irritability, anxiety,
restlessness
Rohypnol
Powerful sleep inducing drug
Schedule I drug – Controlled Substances Act
Banned Benzodiazepine
Made in the U.S. – legal in Mexico