Transcript Perspectives and Achievements with Rational

Perspectives and Achievements
with Rational Pharmacotherapy
Drug Industry and Rational
Pharmacotherapy
Teddy Hebo Larsen
Chairman
Danish Association of the Pharmaceutical Industry
Effect
(Adverse reaction x Price)
What are the aims of
rational
pharmacotherapy?
Savings,
Optimum patient care
or
” value for money”?
”And by our wisdom
so have we progressed
when few have too much
and fewer have too little”
∆ Costs
∆ Effects
The doctors dilemma
• Maximisation of the efficacy of a
therapy
• Minimisation of the risk posed by
the therapy
• Regard for the patient’s right to
choose
• Regard for the economic
consequences/minimising costs
Ekelund, M. 2001
“Pharmaceuticals are highly specialized products, and
individuals respond idiosyncratically to different drugs.
Therefore individual consumers may not agree on the
ranking of a given pharmaceutical in relation to
others, although there is consensus over the general
efficacy or therapeutic benefit of the drug. The
individual reaction to a certain brand (e.g. with regard
to the nature and intensity of its side effects) is often
hard to predict ex ante. For this reason,
pharmaceuticals are, to a high degree, experience
goods whose benefits must be judged after
consumption.”
Johannesson and Lundin
(2001)
”We also find that physician preferences
measured as their prescription history, are
important for the choice of drug. The effect of
physician preferences is strongest among new
patients, since for repeated prescriptions the
effect of physician preferences is mitigated by
patient habit formation that slows down the
diffusion of new drugs”.