Parenteral Administration of Medication in Small
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Transcript Parenteral Administration of Medication in Small
Oral (PO)
Sublingual
Via feeding tube
› Esophagostomy
› Gastrostomy
› Jejunostomy
Aural
Topical
Topical ophthalmic
Transdermal
Intranasal
Inhalation
Orogastric intubation
› Nebulized or
Nasogastric
volatilized
intubation
Intratracheal
Rectal (PR)
o Intradermal (ID)
o Intraosseous (IO)
o Subcutaneous
o Intraperitoneal (IP)
(SC or SQ)
o Intramuscular (IM)
o Intravenous (IV)
o Intra-arterial (IA)
o Epidural/subdural
o Intracardiac (IC)
o Intramammary
Patient Factors
Health conditions
Drug Factors
Type of
medication/fluid
› Symptoms
Formulation of drug
› Absorption rate of
drug required
Cost
Temperament
Systemic vs. local
Ease of administration
effect desired
for client
Does this medication require that special
precautions be followed during
administration (i.e. gloves, mask)?
› Examples?
Potential side effects?
› Pain from injection
› Vomiting/GI upset/constipation
Intramuscular
90
Subcutaneous
45
Intravenous
25
Intradermal
Epidermis
Dermis
Subcutaneous tissue
Muscle
10–15
The skin is made up of three layers: the
epidermis, dermis, and subcutaneous layers
› The epidermis is several cell layers thick and does not
contain blood vessels. Its thickness varies greatly
from region to region in any animal and varies from
species to species.
› The dermis is composed of blood vessels, lymph,
nerve fibers, and accessory organs of the skin (glands
and hair follicles).
› The subcutaneous layer (hypodermis) is composed of
connective tissue and contains a large amount of
fat.
Muscle lies underneath all of these layers
Gather supplies
Needles
Syringe
Medication to be injected
Proficient person to restrain the animal
For venipuncture only:
Cotton ball with alcohol
Hydrogen Peroxide (optional)
Needle gauge is determined by:
› Consistency of drug
› Route of administration
› Patient size
At least two needles are required
› One to draw up the medication
› One to administer the medication
Why is this?
Draw up exact amount of drug
› Can use smallest needle available
Aspirate all drug into the syringe (out of
the needle)
› Hub loss-
Remove needle and replace with
appropriate needle
Carefully ensure all air is out of the
syringe by slowly depressing the plunger.
Supplied as:
› Sterilized solutions
› Powders that must be reconstituted with
sterile solution
May be stored in:
› Vials (single or multi-dose)
› Ampules
› Fluid bags
Common use of ID route:
› Desensitize skin
› Allergy skin testing
Skin is usually shaved before performing
an ID injection
Drug is not dispersed throughout the
body
A fold of skin is lifted or skin is pulled taught
and a 25- to 27- gauge needle attached
to a syringe is inserted with the bevel up
into the dermis.
› If allergy testing: A 0.1 ml volume of allergen is
injected.
› If locally anesthetizing skin: dose of drug
The injection site will look like a translucent
lump if the injection is performed correctly.
Easiest route to perform technically
Common use of SQ route:
› Vaccine administration
› Fluid administration
› Pain medications, antibiotic injections, Insulin
Absorption rate is slow compared to other
routes
› May be slower in obese animals
Some substances are harmful if injected SC
› Example:
Preferred site for most SC injections is the
dorsolateral region from the neck to the
hips.
› The dorsal region of the neck and back should
be avoided for drug administration.
Cat vaccines: the _______________________
should be avoided because of the
incidence of vaccine-induced tumors.
› Feline vaccinations should be administered in
as distal a portion of an extremity as possible.
Fold of skin is tented and the needle is
inserted at the base of the tent.
› Insert needle as if walking INTO the tent
Aspirate
› Why?
After injection, briefly massage skin to
facilitate drug distribution.
Appropriate route for injection of small
volumes of medication.
Common uses of IM route:
› Anesthetics/sedatives
Convenient route of administration for
fractious animals
› Pain medications
› Heartworm treatment
Generally, more painful for animals than
SC or IV.
› Why?
Drugs are most often administered in the:
› Lumbosacral musculature lateral to the
dorsal spinous processes
› Semimembranosus/ semitendinosus muscles
of the rear leg
In the hind limb: needle should enter the
lateral aspect of the muscle and be
directed caudally
› Why?
Deep IM injections in the
third to fifth lumbar region
of the ___________________
are used to administer
adulticide heartworm
treatment (Immiticide®).
Isolate the muscle between the fingers and thumb.
A 22 to 25 gauge needle attached to a syringe is
embedded in the muscle at a ______ angle.
As with a SQ injection, the needle hub is checked
for blood before administration of medication to
make certain a vessel is not inadvertently
penetrated.
› How did we do this?
Once in the muscle, inject the medication slowly.
Massage the site for a few seconds after the
injection to help distribute the substance if possible.
› Exception:
Tissue trauma
Pain at injection site
Nerve damage
Drugs and/or fluids may be injected directly
into a vein or through an IV catheter.
IV route produces an immediate response
› Usually given slowly
Common use of IV route:
›
›
›
›
›
›
Inducing anesthesia
Chemotherapeutic agents
Anti-convulsant drugs
Irritating drugs
Emergency/resuscitation drugs
Large amounts of _________ needed
Requires new needle for administration
CAT
DOG
Cephalic
Lateral saphenous
Cephalic
Medial saphenous
Femoral
Note: The jugular vein is used to administer
injections in small animals IF an intravenous
jugular catheter is in place.
Expel all air bubbles from the syringe prior
to inserting into the vein.
Restrainer should occlude the vessel with
digital pressure or use a tourniquet.
Grasp the extremity and pull the skin taut in a
distal direction.
Swab the skin and hair with an alcohol-soaked
cotton ball (go with the fur).
Insert a 20- to 25- gauge needle, bevel up into
the vein.
Usually blood enters the hub of the needle
at penetration of the vein (flash), BUT,
placement is confirmed by aspirating.
› What should we see?
› Venipuncturist: communicate to restrainer “I’m in”
› Restrainer: release pressure from the vein
Inject the medication into the vein.
› If large volume of drug or movement of needle:
Communicate with restrainer and remove
needle
Apply firm pressure to the injection site until
hemostasis/coagulation occurs
Most common: Nye Tourniquet or Penrose
drain/rubber material
Can be very dangerous if used improperly
Goal is to visualize and palapte vein.
Must be able to remove before injecting!
Injecting drug outside of vein
Hematoma formation
Intra-arterial injection of drug
Hitting a nerve (pain, lameness, paralysis)
Air-embolus
Phlebitis
Septicemia