Pharmacokinetics
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Transcript Pharmacokinetics
Rational Prescribing
&
Prescription Writing
Collected and Prepared
By
S.Bohlooli, Pharm.D, PhD
Introduction
• After reaching to the Diagnosis, the practitioner
can often select from variety of therapeutic
approaches.
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Drug therapy
Surgery
Psychiatric treatment
Radiation
Physical therapy
Health education
Counseling
No therapy
Rational Prescribing
1.
2.
3.
4.
5.
6.
Make a specific diagnosis
Consider the pathophysiologic implications
Select a specific therapeutic objective
Select a drug of choice
Determine the appropriate dosing regimen
Devise a plan for monitoring the drug’s action
and determine an end point for therapy
7. Plan a program of patient education
The Prescription
Elements of the Prescription
1.
Identity of prescriber
•
2.
3.
4.
Date
Name and address of patient
Body of prescription
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5.
6.
Name, license classification, address, office telephone number
Medication, the strength, quantity
Dosage and complete directions for use
Refill information , waiver for child proof and additional
labeling instructions
Prescriber Signature and other Identification Data
Abbreviation Used in Prescriptions & Chart Orders
Prescriptions should be legible, unambiguous, dated and timed
Prescribing Errors
•
Omission of Information
As needed (prn)
•
Poor Prescription Writing
Illegible handwriting
Ambiguous decimal points
•
Inappropriate Drug Prescription
Failure to recognize contraindications by other
disease
Failure to obtain information about other drugs
Failure to recognize possible physicochemical
incompatibility
Compliance
• The extent to which patients follow the treatment
instructions
• Types of noncompliance
The patient fail to obtain the medication
The patient fail to take the medication as prescribed:
wrong dosage, wrong frequency of administration,
improper timing, wrong route or technique of
administration, taking medication for the wrong
purpose
The patient prematurely discontinue the medication
The patient takes medication improperly.
Strategies to improve compliance
• Enhanced communications
• Assessment of personal, social and
economic conditions
• Development of a routine for taking the
medications
• Provision of systems to assist taking
medications
• Mailing of the refill reminders by pharmacist
Labeled and Unlabeled Uses of
Drugs
Socioeconomic factors
• Generic Prescribing
If the physician wants a particular brand of
drug product dispensed handwriting
instruction to “Dispense as written “ is
required.
• Other Cost Factors
Professional service fee
Good Luck