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Chapter 9
Special Types
of Intravenous Calculations
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Intravenous Calculations
• Very potent medications
• Small changes in infusion rate can greatly affect body’s
physiologic response
• Pharmacy usually prepares medications and IV solutions
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Dosage Calculations
• D = Desired dose or order
• H = On hand or have
• S = Supply
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Three Methods of Dosage Calculation
• Proportion expressed as two fractions
• Proportion expressed as two ratios
• Formula method
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Proportion Expressed as Two Fractions
• SUPPLY = X
HAVE
DESIRE
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Proportion Expressed As Two Ratios
• SUPPLY : HAVE :: X : DESIRE
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Formula Method
• DESIRE × SUPPLY = X
HAVE
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Infusion Rates Formulas
• Amount of Drug =
Amount of Drug in 1 mL
Amount of Fluid (mL)
• Total number of units/hour × X mL= mL/hour
Number of units to run
• Total number of mg/hour × X mL= mL/hour
Number of mg to run
• Total number of milliliters ordered = hours
Total number of milliliters/hour
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
The physician has ordered regular insulin 21 units/hour
IV. The medication is available 250 units in 250 mL
normal saline. The insulin IV is being run on an infusion
pump. What is the rate per hour?
A. 19
B. 20
C. 21
D. 22
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
C. 21
– Total number of 21/hour × 250 mL = 21 mL/hour
Number of 250 units to run
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Infusion Formula for Drugs
Ordered in mcg/min
• Reduce the numbers in the standard solution to mg/mL
• Change mg to mcg
• Divide by 60 to get mcg/min
• Use the formula, ratio, or proportion method to solve for
mL/hour
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Infusion Formula for Drugs
Ordered in mcg/kg/min
• To convert lb to kilograms, divide by 2.2
• Reduce the numbers in the standard solution to mg/mL
• Change mg to mcg
• Divide by 60 to get mcg/min
• Use the formula, ratio, or proportion method to solve for
mL/hour
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Question
The physician has ordered dopamine (Intropin) 200
mcg/min IV. The medication is available 400 mg in 250
mL D5W. The dopamine (Intropin) is being run on an
infusion pump. What is the rate in mL/hour?
A. 7
B. 7.5
C. 8
D. 8.5
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Answer
B. 7.5
• Reduce the numbers in the standard solution to mg/mL:
400 mg/250 mL = 1.6 mg/mL
• Change mg to mcg: 1.6 mg × 1000 = 1600 mcg/mL
• Divide by 60 to get mcg/min: 1600 mcg/60 min = 26.67
mcg/min
• Use either the formula, ratio, or proportion method to
solve for mL/hour
200 mcg/min x 1 mL/hour =
26.67 mcg/min
7.5 mL/hour
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Body Surface Area
• Antineoplastic drugs based on body surface area in
square meters
• Mathematical formulas
– Square root of weight (kg) × height (cm) = BSA
3600
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Body Surface Nomogram
• Mark the patient’s height in first column
• Mark the patient’s weight in the third column
• Draw a line between these two marks
• Point at which the line intersects in the middle column
indicates estimated body surface in meters squared
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Body Surface Nomogram
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Patient Controlled Analgesia
• Basal rate: amount of medication infused continuously
every hour
• PCA dose: amount of medication infused when the
patient activates the button control
• Lockout time or delay: feature that sets interval during
which patient cannot initiate another dose after giving a
self dose
• Total hourly dose: maximum amount of medication the
patient can receive in an hour
Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins
Heparin and Insulin Protocols
• Protocols are based on a parameter, usually a lab test
ordered by healthcare provider
• After receiving the lab test results, the nurse uses the
protocol to determine the change in the dosage amount
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