Transcript Circulation

Transport in Animals
• Gastrovascular cavities
– flatworms and cnidarians
• Nutrients and gases can move by processes
such as diffusion and active transport.
Figure 42.1 Internal transport in the cnidarian Aurelia
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No Circulatory System
Hydra
Sponge
Water
Gastrovascular cavity
Water
Nematode
Water
Osculum
(excurrent
opening)
Water
Gastrovascular cavity
Incurrent
pore
Anus
Mouth
Water
Water
Gastrovascular cavity
a.
Open Circulation
Grasshopper
Closed Circulation
Earthworm
Heart
Heart
Lateral
hearts
Hemolymph
b.
c.
Open Circulatory systems
• Insects, other arthropods and most mollusks
• No distinction between blood and the
interstitial fluid
Open Circulatory systems
• Hemolymph
– name of general body fluid
– directly bathes the internal organs
• System of sinuses
• Heart and body movements cause
circulation
Open Circulatory systems
• Slower circulation
• sluggish animals BUT...
– Insects are very active
Figure 42.2 Open and closed circulatory systems
Closed Circulatory Systems
– Earthworms, squids, octopuses, and vertebrates
• Blood is confined to vessels and is distinct
from interstitial fluid
• Consists of the heart, blood vessels and
blood
Blood
• Plasma – about 55% of blood volume
– 90% water
– inorganic salts (electrolytes), metabolites
(vitamins, aa, glucose), wastes & hormones
– proteins
• osmotic balance, viscosity
• buffers, transport lipids, antibodies, clotting factors
(fibrinogen)
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Plasma
Plasma
(92% water, 55%
of whole blood)
Red blood
cells
Platelets and
leukocytes (<1%)
Formed
elements
Platelets
White blood cells
Blood Plasma
Red Blood Cells
Red blood cells
(erythrocytes)
(45% of whole
blood)
Platelets
Plasma proteins (7%)
Albumin (54%)
Globulins (38%)
Fibrinogen (7%)
All others (1%)
4 million–6 million/ 150,000–300,000
mm3 blood
mm3 blood
Water (91.5%)
Other solutes (1.5%) Neutrophils
Electrolytes
Nutrients
Gases
Regulatory
substances
Waste products
Monocytes
3–8%
60–70%
Basophils
0.5–1%
Eosinophils
2–4%
Lymphocytes
20–25%
Figure 42.14x Blood smear
Blood
Cellular Elements:
• Red Blood Cells (Erythrocytes)
– Most numerous (5-6 million in one cubic ml)
– Transport oxygen & carbon dioxide
Blood
Cellular Elements:
• White Blood Cells (Leukocytes)
– Function in body’s defense
– A cubic ml of blood has about 5,000 – 10,000
– in interstitial fluid or in the lymphatic system –
where your body fights pathogens
Blood
Cellular Elements:
Platelets are cell fragments that pinch off from
larger cells in the bone marrow
-Function in the formation of blood clots
Prothrombin
Thrombin
Fibrinogen
Thrombin
Fibrin
1. Vessel is
damaged,
exposing
surrounding
tissue to blood.
2. Platelets
adhere and
become
sticky, forming
a plug.
3. Cascade of
enzymatic
reactions is
triggered by
platelets,
plasma factors,
and damaged
tissue.
4. Threads of
fibrin trap
erythrocytes
and form
a clot.
5. Once tissue
damage
is healed,
the clot is
dissolved.
Figure 42.16x Blood clot
Heart
• one atrium or two atria
• one or two ventricles
Heart
• one atrium or two atria
– chambers that receive blood returning to the
heart
• one or two ventricles
– chambers that pump blood out of the heart.
Blood vessels
• Arteries
– branch into arterioles
• Capillaries
• Veins
– venules merge into veins
Blood vessels
• Arteries
– branch into arterioles
– carry blood away from heart
• Capillaries
– materials are exchanged
• Veins
– venules merge into veins
– carry blood back toward heart
Blood Vessel Structure
• Walls of arteries or veins have three layers:
–
–
–
–
epithelium
smooth muscle with elastic fibers
connective tissue
Arteries have thicker walls than veins
• Capillaries only have the inner epithelium
layer
Capillary Exchange
• Law of Continuity
– blood flows slowly in capillaries because larger
total cross-section
– allows materials to be exchanged
Figure 42.10 The interrelationship of blood flow velocity, cross-sectional area of
blood vessels, and blood pressure
Capillary Exchange
• About 85% of the fluid that exits capillaries
re-enters at the venule end.
Return of Blood to Heart
• Pressure too low in veins
• contraction of skeletal muscles move blood
• one-way valves in veins prevent backflow
Variation in Vertebrate
Circulation
FISH
• Two chambered heart and a single circuit of
blood flow
Vertebrate Circulatory Systems
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Systemic
capillaries
Atrium
Respiratory
capillaries
Gills
Body
Sinus
venosus
Ventricle
Conus
arteriosus
Variation in Vertebrate
Circulation
AMPHIBIAN
• Three chambered heart (two atria and one
ventricle) and double circulation (two
circuits of flow)
Amphibian Circulation
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Truncus arteriosus
Carotid artery
Systemic artery
Lungs
Aorta
Pulmonary
capillaries
Pulmocutaneous
artery
Right atrium
Conus
arteriosus
Left atrium
Right atrium
Conus
arteriosus
Ventricle
Pulmonary vein
Sinus venosus
Left atrium
Ventricle
Posterior vena cava
Systemic
capillaries
Body
a.
b.
Variation in Vertebrate
Circulation
AMPHIBIAN
• Pulmonary circuit
– blood is pumped to the lungs, where it is
oxygenated and carried back to the left atrium
• Systemic circuit
– blood is pumped to the rest of the body, where
it gives up oxygen and is carried back to the
right atrium
Variation in Vertebrate
Circulation
AMPHIBIAN
• Double circulation assures a vigorous flow
of blood to the vital organs
• single ventricle --some mixing of oxygenrich and oxygen-poor blood.
Variation in Vertebrate
Circulation
MAMMALS & BIRDS
• Have a four chambered heart and double
circulation
• The left side of the heart handles oxygenrich blood and the right side handles only
oxygen-poor blood.
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Head
Systemic
capillaries
Aorta
Superior
vena cava
Lungs
Pulmonary artery
Pulmonary
veins
Left atrium
Pulmonary
semilunar valve
Bicuspid
mitral
valve
Right atrium
Tricuspid
valve
Respiratory
capillaries
Pulmonary
artery
Superior
vena cava
Pulmonary
vein
Aorta
Inferior
vena cava
Artery
Left
ventricle
Right ventricle
Body
Inferior
vena cava
Systemic
capillaries
a.
b.
Mammalian or Bird Heart
• Valves prevent backflow of blood when the
ventricles contract
– Between each ventricle and atrium is an
atrioventricular (AV) valve
• tricuspid and bicuspid (mitral)
– At the exits of the heart are the semilunar
valves
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Head
Systemic
capillaries
Aorta
Superior
vena cava
Lungs
Pulmonary artery
Pulmonary
veins
Left atrium
Pulmonary
semilunar valve
Bicuspid
mitral
valve
Right atrium
Tricuspid
valve
Respiratory
capillaries
Pulmonary
artery
Superior
vena cava
Pulmonary
vein
Aorta
Inferior
vena cava
Artery
Left
ventricle
Right ventricle
Body
Inferior
vena cava
Systemic
capillaries
a.
b.
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Right atrium
Left atrium
SA node
(pacemaker)
AV node
Internodal
pathway
AV
Interventricular septum
AV bundle
AV bundle
Purkinje fibers
Left and right
bundle branches
Purkinje fibers
2. The impulse is delayed at the AV node. It
then travels to the AV bundle.
1. The impulse begins at the SA node and travels to the
AV node.
AV bundle
Interventricular
septum
3. From the AV bundle, the
impulse travels down the
interventricular septum.
Left and right
bundle branches
4. The impulse spreads to
branches from the interventricular septum.
Purkinje fibers
5. Finally reaching the Purkinje fibers,
the impulse is distributed throughout
the ventricles.
R
The control of heart rhythm
Millivolts
+1
P wave
T wave
0
Q
S
1 sec
-1
Seconds
Cardiac Cycle
• a complete sequence of the heart
contracting to pump blood, relaxing to fill
with blood.
• total length is about 0.8 s
– The contraction phase is called systole
– The relaxation phase is called diastole
Figure 42.6 The cardiac cycle
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Blood pressure
gauge
100 150
50
200
0 250
100 150
50
200
0 250
100 150
200
50
0 250
Cuff
Stethoscope
1. Cuff pressure: 150 mm Hg
No sound:
Artery closed
2. Cuff pressure: 120 mm Hg
Pulse sound:
Systolic pressure
3. Cuff pressure: 75 mm Hg
Sound stops:
Diastolic pressure