leukocytes - Stari web

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Transcript leukocytes - Stari web

Dora Bračko, 2nd year
2013/2014
Mentor: A. Žmegač Horvat
LEUKOCYTE
white
cell
part of the immune system
 infection, foreign materials


7000 to 9000 cells per µL of blood  1%
AGRANULOCYTES
(MONONUCLEAR)
GRANULOCYTES
(POLYMORPHONUCLEAR)
NEUTROPHIL GRANULOCYTE
62%
 multi-lobed nucleus
 bacterial or fungal infections
 first responder
 phagocytosis of bacteria

EOSINOPHIL GRANULOCYTE
2.3%
 bi-lobed nucleus; cytoplasm full of granules
 parasitic infections
 allergic reactions

BASOPHIL GRANULOCYTE
0.4%
 bi- or tri-lobed nucleus; large granules
 allergic and antigen response
 histamine

LYMPHOCYTE
30%
 nucleus eccentric in location
 immune response
 B cells, T cells, natural killer cells

MONOCYTE
5.3%
 kidney-shaped nucleus
 phagocytosis
 presentation of pieces of pathogens to T cells
 in tissues  macrophages

FIXED LEUKOCYTES

migrate into body tissues
 Kupffer
cells
 histiocytes
 dendritic cells
 mast cells
 microglia
DISORDERS


quantitative
 proliferative
(leukocytosis): neutrophilia, eosinophilia
 leukopenia:
neutropenia, lymphocytopenia
qualitative
 volume,
conductivity, granularity
REFERENCES
http://en.wikipedia.org/wiki/White_blood_cell
 http://www.britannica.com/EBchecked/topic/3
37728/white-blood-cell
 http://health.howstuffworks.com/humanbody/systems/circulatory/blood2.htm
