Transcript Vaccinology Jeopardy.

VACCINOLOGY
JEOPARDY!
2010
Application Definitions
TieBreakers
Concepts
Facts
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1-1-Q
Antibodies can be produced against
almost any substance…
TRUE OR FALSE?
1-1-A
TRUE
1-2-Q
The more similar a vaccine is
to the natural pathogen, the
better the immune response to
the vaccine…
TRUE OR FALSE?
1-2-A
TRUE
1-3-Q
All vaccines present
modified/selected antigen(s) that
induce an immune response without
causing INFECTION…
TRUE OR FALSE?
1-3-A
FALSE
1-4-Q
Humoral and cell-mediated immune
responses CANNOT occur at the
same time…
TRUE OR FALSE?
1-4-A
FALSE
FALSE
1-5-Q
Which of the following statements are
true of acquired, but not innate
immunity?
(a) Involves cytokines and complement
(b) Can be induced by vaccine
(c) Key mechanism is to prevent injury
and death from infection
(d) Gets stronger over time
1. a and c
2. b and d
3. a, b, and c
1-5-A
2. b and d
2-1-Q
Some antibodies coat organisms,
making them more readily ingested
by phagocytes…
TRUE OR FALSE?
2-1-A
TRUE
2-5-Q
T-cell independent
responses usually produce
immunological memory?
TRUE OR FALSE?
2-5-A
FALSE
2-4-Q
What type of response is
depicted here?
(a) T-cell independent
(b) T-cell dependent
B*
B
B*
IgM
2-4-A
(a) T-cell independent
2-3-Q
Factors that affect the immune
response include:
(a) Route of vaccine administration
(b) Presence of maternal antibody
(c) Characteristics of the antigen
(d) Host’s nutritional status
1. b, c, and d
2. b and c
3. a, b, c, and d
2-3-A
3. a, b, c & d
2-2-Q
Daily Double
Functions of the complement system include:
(a) cell lysis
(b) attracting phagocytes to the site of
inflammation
(c) coating antigens to make them more
susceptible to phagocytosis
(d) promoting inflammation
1. a, b, c, & d
2. a, b & c
3. a & d
2-2-A
1. a, b, c & d
3-3-Q
Interruption of a series of
vaccinations does not require
starting the series over again,
regardless of the interval elapsed.
TRUE OR FALSE?
3-3-A
TRUE
3-1-Q
If two live parenteral vaccines are
given 14 days apart, the vaccine
that was given first should be
repeated 28 days later.
TRUE OR FALSE?
3-1-A
FALSE
3-4-Q
A live oral vaccine and a live
injectable vaccine must be
administered on the same day or
one month apart.
TRUE OR FALSE?
3-4-A
FALSE
5-4-Q
What vaccines should NOT be given to a
perinatally HIV-infected toddler with a
normal CD4 count and no history of
opportunistic infections?
(a)
(b)
(c)
(d)
MMR
Varicella
Hepatitis B
Pneumococcal Conjugate
1. b
2. a and b
3. None of the above
5-4-A
3. None of the above
5-1-Q
If a person will be having a
splenectomy in 2 week’s time, it is
too late to immunize them with the
recommended vaccines.
TRUE OR FALSE?
5-1-A
FALSE
4-5-Q
The immunoglobulin that
predominates in the secondary
immune response
(a)
(b)
(c)
(d)
IgM
IgG
IgA
IgE
4-5-A
(b) IgG
4-4-Q
This type of vaccine stimulates
B cells without the help of T cells
(a) Conjugated polysaccharide
vaccine
(b) Pure polysaccharide vaccine
(c) Recombinant vaccine
4-4-A
(b) Pure polysaccharide
vaccine
4-1-Q
Lymphocytes that mediate cellmediated immunity are called ...
(a) T-lymphocytes
(b) B-lymphocytes
(c) T4 lymphocytes
4-1-A
(a) T-lymphocytes
4-2-Q
These are non-antibody proteins
that function as chemical
messengers that regulate all
immune responses.
(a) Antigen-presenting cells (APCs)
(b) Cytokines
(c) Complement
4-2-A
(b) Cytokines
4-3-Q
Daily Double
A cascade of blood proteins that
can destroy foreign or infected
cells.
(a) Interleukins
(b) Complement
(c) Natural killer cells
4-3-A
(b) Complement
3-2-Q
Vaccine doses given at less than
the recommended interval may
result in less than optimal antibody
response and should not be counted
as part of a primary series.
TRUE OR FALSE?
3-2-A
TRUE
3-5-Q
Simultaneous administration of a
passive immunizing agent (E.g.
immune globulin) and an
inactivated vaccine is not
recommended for post exposure
prophylaxis.
TRUE OR FALSE?
3-5-A
FALSE
5-3-Q
Inactivated vaccines are not likely
to be affected by circulating
maternal antibodies.
TRUE OR FALSE?
5-3-A
TRUE
5-5-Q
How do premature infants differ from
full term infants in terms of when,
after birth, they should be
immunized with DTaP-IPV-Hib?
(a) They don’t differ – they should be
immunized at the same chronological
age as full-term infants
(b) They should be immunized at the
age that adds on for their number of
weeks of prematurity
(c) They should weigh at least 2000g.
5-5-A
(a) They don’t differ – they
should be immunized at
the same chronological age
as full-term infants
5-2-Q
Cell-mediated immunity is mediated
by B lymphocytes….
TRUE OR FALSE?
5-2-A
FALSE
Final Jeopardy
NOTE: Can wager up to
full total of team’s
points!
Final Jeopardy
An accelerated, memory immune
response to an antigen is also
referred to as the _________
response.
(a) Anergic response
(b) Anamnestic response
(c) Arthus response
(b) Anamnestic response