Transcript Green Health Technology

Professor Dr. Her Royal Highness Princess Chulabhorn
Chulabhorn Research Institute (CRI), Thailand
Science and Technology for the Improvement of the Quality of Life
• The inherent function of the scientific endeavour
is to carry out a comprehensive and thorough
inquiry into nature and society, leading to new
knowledge.
• The new knowledge provides educational,
cultural and intellectual enrichment and leads to
technological advances and economic benefits.
• Promoting fundamental and problem-oriented
research is essential for achieving endogenous
development and progress.
Chulabhorn Research Institute
A unique mission:
• to establish a program of scientific research
and education of international standard that
would significantly contribute to the
development of the country and specifically
to the quality of life of its people.
Chulabhorn Research Institute (CRI)
• Research has aimed to find solutions to local
and regional environmental and health
problems and to improve our knowledge of
indigenous natural resources.
Chulabhorn Research Institute (CRI)
• The building of scientific capacity should be
supported by regional and international
cooperation, to ensure both equitable
development and the spread and utilization of
human creativity without discrimination of any
kind against countries, groups or individuals.
• Cooperation between developed and developing
countries should be carried out in conformity with
the principles of full and open access to
information, equity and mutual benefit.
Chulabhorn Research Institute (CRI)
Activities focus on 3 major areas:
• Research
• Education/Training and
Scientific Exchange
• Special Projects and Programs
Priority research is undertaken in the
following areas:
• Natural Products,
Medicinal Chemistry and
Organic Synthesis
• Environmental Toxicology
• Biomedical Research
• Biotechnology
Education/Training and Scientific Exchange
 Worldwide measures have been
undertaken to promote basic education
for all.
 Scientific knowledge be imparted and
transferred to all, particularly to a rural
population with low educational
background.
• The development of human resources is
one of the key activities of the Institute.
• CRI has initiated a number
of education and academic
training programs in
specialized areas.

Post-graduate education

Training courses

Seminars, symposia, workshops and conferences
Education/Training and Scientific Exchange
 The fundamental role played by women in
the application of scientific development
to food production and health care must
be fully recognized
 Efforts should be made to strengthen their
understanding of scientific advances in
these areas.
“Green Health Technology”
for Women’s Empowerment and Sustainable
Development in Thailand
 The project was
designed to show how
high levels of science
and technology may be
applied and transferred
to a rural population
with low educational
background.
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Two major kinds of activities were
conducted in parallel:
 Scientific and technological activities
at the CRI laboratories
- the knowledge production part
 Practical activities at the rural
community level - the knowledge
consumption part
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Participants are trained in appropriate technologies for
optimizing growth and producing useful products from
cultivated plants.
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A workshop on the demonstration of the method of
preparing medicinal plants for treating simple illnesses
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Two indigenous Thai herbs with
recognized medicinal properties:
 Curcuma longa, commonly known as
tumeric, but also called curcumin in
Thailand,
 Andrographis paniculata
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Curcuma longa
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Andrographis paniculata
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Women participated in
the Green Health Project
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Physical examinations and medical consultation
Training and instruction in the general areas of health and social skills
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Group activities to improve personal attitudes,
interpersonal skills and ability to work as a team
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A participant coordinating committee was formed by vote
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A training session on the harvesting of Curcuma longa ’s rhizome,
cleaning, drying and packaging by using good manufacturing practices.
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A training course on primary health care in the use of
common household medicine from both medicinal plants
and modern pharmaceutical products.
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Training was offered in basic marketing and management, including
simple accounting practices, to aid in the successful and profitable
sale of medicinal products derived from the project.
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Contributions from the CRI laboratories:
 Initial soil and water analyses using Atomic
Absorption Spectrometry to ensure that levels of
heavy metal contaminants did not exceed the
safe limits.
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CRI laboratories:
 Gas Chromatography of soil and water for
contaminating pesticides.
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CRI laboratories:
 Thin Layer Chromatography
and other techniques
to quantitate active
ingredients in plants.
Chromatograms of A. paniculata product
AP1
AP3
AP4
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CRI laboratories:
 Determining conditions for
seed germination, planting
time, growth period and
harvest time.
 Development and transfer of scientific and
technological know-how to the village
community.
 Analysis and monitoring of the content of
curcuminoids and volatile oils in Curcuma longa.
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CRI laboratories:
 Refining techniques
for isolation,
purification and
structural
characterization of
andrographolide and
derivatives, using
modern technologies
such as, HPLC, NMR,
and MS.
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CRI laboratories:
 Studies of the pharmacological properties of
partially purified extracts and pure compounds
isolated from A. paniculata.
Organ Bath System
Spectrophotometer
Malaria Culture
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CRI laboratories:
 Use of purified Andrographis active compounds as
standards for evaluating the quality of products.
O
Three Active Diterpenoid
Compounds from
HO
Andrographis paniculata
O
O
CH 3
O
CH 2
O
O
CH3
HO
HOH2C
CH2
HO
HOH2C
CH 3
H
CH 3
AP1: Andrographolide
H
CH 3
AP3: 14-Deoxy-11,12-didehydro
andrographolide
HOCH 2
OH
OH
H2C
O
CH 2
H
CH 3
O
OH
AP4: Neoandrographolide
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The Green Health project conducted in
Sra-Kaew Province of Thailand was
considered highly successful.
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Perceived benefits include:
 Greater awareness, changed behavior and
attitudes to agricultural practices and to
concepts of green health.
 Greater interest and ability in health care for
participants and their families, as well as use
of green health products for health care.
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Perceived benefits include (con’t):
 Realization through experience of the value of
keeping records and planning to achieve
success and economic gain.
 Understanding the importance of quality.
 Understanding the value of cooperation to
achieve a common goal within the community.
 Greater self-esteem and confidence.
 Learning a new way to supplement income.