The Cell Cycle

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Transcript The Cell Cycle

Monday 11/2/2015
Agenda: Cell Cycle and Division!
 Review of cells and organelles
 Activity: Catching some Killer Rays
Homework:
 Catching some Killer Rays Worksheet due
Tuesday 11/3/2015 for 30 Points
What do we already know?
• Prokaryotic VS Eukaryotic
cells
• Humans have Eukaryotic
cells
• All cells have organelles
(parts)
• Each organelle has a
function (job)
Catching Some Killer Rays
• Explain why skin cancer might be more prevalent in
California than in Arizona.
• In 2009, it was reported that new melanoma cases
(dangerous form of skin cancer) was identified nearly 75%
higher in men than women. Explain why some people
can survive skin cancer, while others can’t.
http://www.epa.gov/sunwise/doc/az_facts_web.pdf
Handout- Catching Some Killer Rays (Sci. Ntbk)
Catching Some Killer Rays
• You will be annotating the main paragraph (the larger
paragraph in the center)
• You are to complete the worksheet questions using the
textbook from pages 125-127.
Tuesday 11/3/2015
Agenda: Cell Cycle and Division!
 Notes: Cell Cycle and Chromosomes
 Activity: Active Cancer Reading and
Concept Map
Homework:
 Cancer Active Reading and Concept Map due
Wednesday/Thursday 11/4-11/5/2015 for 20 Points
Cell Cycle Reading Review
1. Define cancer and give an example
2. Explain the role of the checkpoints in the cell cycle
3. Describe what the term “melanoma” means?
4. What does the “G” stand for in the cell cycle?
5. In which stage is the nuclei divided?
6. In which stage is the cytoplasm divided?
Cell Cycle & Cellular
Division learning goal
“I can describe the purpose, phases and processes of
cellular reproduction”! 
The Cell Cycle
http://www.nobel.se/medicine/laureates/2001/press.html
Cell Cycle cut-out
Cell Cycle
• G1- “Growth” phase. A cell grows quickly; largest part
of the cycle. The beginning phase of cell division.
• S- “Synthesis” phase; cell’s DNA is copied. Each
chromosome consists of 2 chromatids attached at the
centromere
• G2- “Second Growth” phase. Cell prepares for the
nucleus to divide. A cell will spend nearly 90% of its
life in stages G1 – G2!
• M- “Mitosis” phase; nucleus is divided into 2 nuceli.
Each nucleus has same number of chromosomes.
• C- “Cytokinesis” The cytoplasm divides and 2 NEW
CELLS ARE FORMED 
Cell Cycle cut-out
“S” Phase: Chromosome Diagram
•
https://outlook.office.com/owa/redir.aspx?REF=eeJqM6wom2zYMC13aL1diDjRNdX4hJDv0VFDH541q5w7wYGsePSCAFodHRwczovL3d3dy55b3V0dWJlLmNvbS93YXRjaD92PWxwQWE0VFdqSFE0
Cancer- Active Reading
This is due Tomorrow for
20 Points!!
• You are to annotate
each paragraph 4
times
• Fill in the concept
map on the back
• Answer the questions
and complete the
vocabulary section!
Wednesday/Thursday
11/4-11/5/2015
Agenda: Cell Cycle and Division!
 Activity: Plate Full of Knowledge
 Notes: Stages of Mitosis
 Activity: Begin Mitosis Foldable
Homework:
 No Homework Tonight!
Plate Full of Knowledge: Cancer
& the cell cycle
• http://science.education.nih.gov/supplements/nih1/cancer/activiti
es/activity2_animations.htm
Each person in your group is responsible for
adding “scoops” (answers) to your plate, based on
each video.
You will place your “scoop”, on the proper section
of your plate, creating… a plate full of knowledge 
-Cancer & the Cell Cycle activity- gradebook
Cancer & The Cell Cycle: Plate Full of KnowledgeQuestions
Video 1
Scoop1: Describe the rate of cells
Scoop 2: Describe how cancer cells grow
Video 2
Scoop 1: Describe the “cell clock”
Video 3
Scoop 1: What are tumor suppressor genes?
Scoop 2:Describe their importance
Video 4
Scoop 1: What are mutations?
Cancer and the Cell Cycle
Class discussion:
Video 1
Scoop1: Describe the rate of cells
Scoop 2: Describe how cancer cells grow
Video 2
Scoop 1: Describe the “cell clock”
Video 3
Scoop 1: What are tumor suppressor genes?
Scoop 2:Describe their importance
Video 4
Scoop 1: What are mutations?
Q2 WK2 D2
MITOSIS
When is mitosis used?
• Mitosis: reproduction of somatic (body) cells = cellular
division
• Diploid: full # of chromosomes (2n) = 46
• Haploid: half # of chromosomes (n) = 23
• Somatic Cells (body cells) are Diploid
• Gametes (sex cells) are Haploid
Stages of Mitosis
•Prophase
•Metaphase
•Anaphase
•Telophase
Interphase: The cell prepares for division
• What happens…?
• DNA replicates
• Organelles replicate
• Cell increases in size
Interphase
Animal Cell
Plant Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Prophase: The cell prepares for nuclear division
• What happens…?
• DNA condenses into
chromosomes, spindles
form & nuclear envelope
dissolves. The
chromosomes
become visible
Prophase
Animal Cell
Plant Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Metaphase: The cell prepares
chromosomes for division
• What happens…?
• Chromosomes line
up at the center of
the cell
• Spindle fibers attach
from daughter cells
to chromosomes at
the centromere
Metaphase
Animal Cell
Plant Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Anaphase: The chromosomes divide
• What happens…?
• Spindle fibers pull
chromosomes apart
• ½ of each chromosome
(called chromatid)
moves toward opposite
pole
Anaphase
Animal Cell
Plant Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Telophase: The cytoplasm divides
• What happens…?
• DNA spreads out
• 2 nuclei form
• Spindles dissolve
• Cell membrane
pinches in and
forms the 2 new
daughter cells
Telophase
Animal Cell
Plant Cell
Photographs from: http://www.bioweb.uncc.edu/biol1110/Stages.htm
Cytokinesis: Final step in division
• What happens…?
• Cytokinesis occurs when
the cleavage furrow
appears
• Division of the cytoplasm
• 2 identical daughter cells
form