Transcript bilateral acute anterior uveitis associated to sapho - GEMU-SEDU

Castaño Martín B , Rubio Álvarez N, Vleming Pinilla E, Muñoz
Gutierrez B
Hospital Universitario Príncipe de Asturias, Alcalá de Henares,
Madrid.






35-year-old woman.
PH: hypothyroidism, chronic espondiloarthropathy and acute anterior
uveitis outbreaks in Romania.
Complaints right and painfull red eye.
BM: Tyndall 3+, posterior synechiae and retrokeratic pigmentary
deposits .
No findings in ocular fundus, IOP and VA.
Diagnosis: right unilateral anterior uveitis.
• Systemic assessment: HLA-B27 + and past HBV serology, the rest
analysis were negative including Mantoux test. Radiology of sacroiliac
joints showed bone step with joint effacement(FIG.1)
FIGURE 1: radiology of sacroiliac joints
•A year later she presented bilateral acute anterior uveitis.
•
In the next 4 month, she presented pustular lessions in palms
(FIG.2) and hidradenitis suppurativa. Dermatology Service diagnosed
it as SAPHO syndrome.
FIGURE 2: pustular lessions in palms
•
•
She presented 3 alternating episodes of UAA in both eyes in 2014
and worsening of the systemic disease. Treatment with metotrexate
was not enough to control the simptoms and together, with the
reumatologist ,we decided to associate treatment with Golimumab.
Currently, she remains asymptomatic