Transcript Gold Eyelid Weight Implants

Processed Amniotic
Membrane
Allografts
Amniotic Membrane Allografts
What is Human Amniotic Membrane?
• A unique, avascular
membrane separating the
mother from the fetus.
• Provides an incubating
environment promoting
cellular differentiation.
• Provides an immunological
barrier to prevent “foreign
body” rejection.
Photo: Courtesy of Juan Batlle, M.D.
Anatomical Profile: AM
Anatomy of the Ocular Surface
(1) Conjunctival
Epithelium
(2) Corneal
Epithelium
(6) Limbus –
Stem Cells
History of AM in Ophthalmology
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De Rotth. conjunctival defects (1940).
Lavery. lime burn of conjunctiva and cornea (1946).
Sorsby et al. caustic soda burns (1947).
ALLOTRANSPLANTAT [late 80’s USSR->Venezuela, DR]
• Batlle and Perdomo. Conjunctival substitute with placental
allotransplant. Scientific Poster 25. American Academy of
Ophthalmology meeting. Chicago, IL USA. October 1993.
• Kim and Tseng. Transplantation of preserved human
amniotic membrane for surface reconstruction in severely
damaged rabbit corneas. Cornea 14:473-84, 1995. [
Surgical Indications: AM
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Pterygium Excision
Corneal Ulcerations/Perforations
Chemical/Thermal Burns
Bullous Keratopathy
Ocular Dermoids/Tumors
Fornix Reconstruction/Symblepharon
Stem Cell Transplants
Pterygium
• A mutated growth on
the surface of the eye
• Requires surgical
excision and placement
of graft
Corneal Ulcerations/Perforations
• A break or defect in
corneal epithelium
• Often secondary to
other systemic
diseases.
Chemical/Thermal Burns
• Chemical burns often
caused by alkali
• Potentially devastating
trauma to surface of
the eye
• Limbal graft possibly
indicated
Bullous Keratopathy
• Edema of the corneal
endothelium
• Very common and
usually affects
individuals over 50
years of age.
Dermoid/Tumor Removal
• Benign congenital
tumors containing
foreign tissue
• Commonly found at the
limbus
Fornix Reconstruction
• Fibrous tract that
connects bulbar conj to
conj of eyelid
• Secondary to other
acquired or traumatic
conditions
• Required
reconstruction of ocular
surface and eyelids
Photo: Courtesy of Juan Batlle, M.D.
Surgical Techniques: AMT/Pterygium
AmbioDry2 Overview
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Tested & Safe
Dehydrated
Terminally Sterilized
Strict, qualitycontrolled protocols
• Device-like quality
AmbioDry: Safe & Viable
• Intact epithelial cell
layer
•Intact dense
connective, basement
membrane
• Presence of loose
fibroblast network
AmbioDry: Logistical Features
• Storage: Room-temp
• No freezer required
• No dry ice shipments
• Simple prep: No soaks
or rinses
• IOP Customer Service:
24 Hrs/7 Days
AmbioDry: Surgical Advantages
• Substrate-free
• Dry-state handling &
trimming
• Visual orientation
identification
• No tears or buttonholes
• Device-like tissue
quality
AmbioDry Configurations
• 1 x 2 cm
• 2 x 3 cm
• 4 x 4 cm
Reimbursement Codes
Supply Code: V2790
CPT Code: 65780 Ocular surface
reconstruction; amniotic membrane
transplantation
AmbioDry & Tisseel
The sutureless approach to eye
surgery.
Fibrin (biological) adhesive
Eliminates sutures
Reduces surgical time
Improved patient care
Better healing
AmbioDry & Tisseel Video