Transcript Предложение к сотрудничеству

1 Department of head and neck tumors, SRI of pediatric oncology and hematology of N.N.Blokhin Cancer Research
Center RAMS, Moscow, Russian Federation
2 Pathology Anatomy, SRI of clinical oncology of N. N. Blokhin Cancer Research Center RAMS, Moscow, Russian
Federation
3 Department of Ocular Oncology and Radiology, Moscow Helmholtz Research Institute of Eye Diseases, Moscow,
Russian Federation
4 Pathology Anatomy, Moscow Helmholtz Research Institute of Eye Diseases, Moscow, Russian Federation
5 Department of chemotherapy of hemoblastoses, SRI of pediatric oncology and hematology of N.N.Blokhin Cancer
Research Center RAMS, Moscow, Russian Federation
6 Department of BMT, SRI of pediatric oncology and hematology of N.N.Blokhin Cancer Research Center RAMS,
Moscow, Russian Federation
The case of the combined surgical approach for extraocular
retinoblastoma
Tatiana Ushakova. 1, Svetlana Saakyan 3, Igor Dolgopolov 6, Tatiana Gorbunova 1, Olga
Gorovtzova O. 1, Rodion Fu 1, Alla Pavlovskaya 2, Inna Horoshilova-Maslova 4,
Evgeniya Stolyarova 5, Vladimir Polyakov 1.
Purpose
To reduce the risk of metastasis for extraocular RB
with preсhiasmatic invasion of the optic nerve using
of the combined neuro-ophthalmological operations
for a maximum radical surgery.
Methods
Before treatment
Unilateral RB with
preсhiasmatic tumor invasion
of the optic nerve was
detected in a boy of five years
in May 2012 based on
ophthalmic examination,
ultrasound and MRI.
SIAC
Methods

The patient had neoadjuvant chemotherapy and after it achieved part reduction of
intraocular tumor and the presence of physiological symmetric contrast both of the
optic nerve according to MRI.
Before treatment
After 3 cycles CVC
Methods

Combined surgical intervention performed in the volume of preсhiasmatic resection
of the optic nerve and enucleation of the left eye followed by chemoradiotherapy.
orbitozygomatic approach
Results and Conclusions
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It is necessary to note the presence of therapeutic
pathomorphosis found in histological preparations of the
eye and the optic nerve in the form of gliosis as
substitution reactions to treatment.
The patient is alive with a period of follow-up of 16
months.
This experience shows the possibility of the improved
control after using the combined surgery RB with
preсhiasmatic invasion of the optic nerve.
Thank you very much for your attention