Transcript Document
Celiac Disease By: Cari Cooper Free Powerpoint Templates Page 1 Basic Facts at Celiac Disease Celiac disease has risen by over 5 times since 1950. 1 in 133 Americans have Celiac disease. Up to 95% of CD patients being undiagnosed or misdiagnosed Free Powerpoint Templates Page 2 What is Celiac Disease ? It is a chronic autoimmune disease It is triggered by gluten proteins found in (wheat, barley and rye) in those genetically susceptible Can affect the gut, skin, joints, uterus, brain, heart and other organs Free Powerpoint Templates Page 3 Epidemiology Free Powerpoint Templates Page 4 Risk factors of CD Being Caucasian Having a positive family member with CD. Commodity with Type 1 diabetes, Thyrodiditis and Hepatitis. Free Powerpoint Templates Page 5 Onset of CD Onset can happen at any time but usually in early childhood Symptoms can vary depending on age. Typical symptoms can be abdominal pain, weight loss, muscle wasting, vomiting, irritability, abdominal bloating and Free Powerpoint Templates Page 6 many more. Rash on a 4 year old with CD Free Powerpoint Templates Page 7 Cancer is the # 1 concerning complication !!! Adults with CD are 3 times more at risk of nonHodkin lymphoma Also increased risk of gastrointestinal cancer and iron deficiency anemia (due to malabsorbtion). Free Powerpoint Templates Page 8 Biomedical Free Powerpoint Templates Page 9 Prevelance Prevelance of Celiac Disease in the US is 75% with some experts estimating 1% Free Powerpoint Templates Page 10 More on CD… More common in women. Found in all races and nationalities Not more common in unhealthy people or people with lower incomes. Free Powerpoint Templates Page 11 How to find out if you have CD ? A blood antigen test to determine both human leukocyte antigen DQ2 and DQ8 Free Powerpoint Templates Page 12 Environmental Factors Free Powerpoint Templates Page 13 Gluten Gluten is a protein comprised of two fractions, glutamine and proline. These fractions are particularly resistant to photolytic digestion. Free Powerpoint Templates Page 14 Increase in gluten Some amounts of gluten are found in spelt naturally however, due to genetic modification gluten has increased by 500 times in “wheat’ Free Powerpoint Templates Page 15 Changes in wheat over time Free Powerpoint Templates Page 16 Unfortunately the main culprit of CD is manmade Free Powerpoint Templates Page 17 Social and Behavioral Free Powerpoint Templates Page 18 Social and Behavioral Factors Relief being the number 1 emotion upon getting a diagnosis of CD !! Free Powerpoint Templates Page 19 Other emotions with CD 71 % of people with CD report either fear, anger, sadness reassurance or resignation ButFree anger is the #1 emotion when it Powerpoint Templates comes to diet restrictions! Page 20 Effects of CD Higher rate of both depressive disorder and disruptive disorder in adolescents 14 % of people granted disability pension in people with CD vs 7% in people without CD Free Powerpoint Templates Page 21 Biostatistics Free Powerpoint Templates Page 22 All types of statistics collected Typical studies on CD : study CD in different races and nationalities, women and in difference in children Some unique studies: allergies, commodities and even flatulence Free Powerpoint Templates Page 23 Health Policy Free Powerpoint Templates Page 24 FDA establishes food labeling for gluten As of 2007 there are four requirements to consider a food to be considered gluten free it must include: 1. an ingredient that is any type of wheat, rye, barley or crossbreeds of these grains. Free Powerpoint Templates Page 25 FDA (continued)… 2. an ingredient derived from these grains and that has not been processed to remove gluten 3. an ingredient derived from these grains, if it results in the food containing 20 or more parts per million (ppm). Powerpoint Templates 4. 20Free ppm or more gluten. Page 26 Help for people with CD National Foundation for Celiac Awareness (NFCA) Emotional Adjustment for Parents (support group) Tax deductions to help with higher costs of foods and preparation Free Powerpoint Templates Page 27 Thank You !! Free Powerpoint Templates Page 28 References • Fotoulaki, Maria; Nousia-Arvanitakis, Sandra; Augousitdou,-Savvopoulou, Persephone, ( Oct 199), Clinical application of immunological markers as monitoring tests in celiac disease, Digestive Diseases and Sciences, pg. 2133-8. De Rosa, Antonio; Troncone, Alda, Vacca, Manuela, ( Jul 2004) Characteristics and Quality of Illness Behavor in Celiac Disease, Psychosomatics, pg . 336-42. Ludvigsson, Jonas; Ludvigsson, Johnny; Ekbom, Anders; Montgomert, Scott, (Nov 2006), Celiac Disease and Risk of Subsequent Type 1 Diabetes: A population cohor study of children and adolescents, Diabetes Care pg. 2483-8 Pediatric Health 4.3 (Jun, 2010): 321-328. Celiac disease and the gluten-free diet. Martin, Suzanne. Journal of the American Academy of Nurse Practitioners 20.5 (May 2008): 243-250. Against the grain: An overview of celiac disease. Martin, Suzanne. Clinical Chemistry 54.2 (Feb, 2008): 444-445, Disease Refractory to a Gluten-free Diet/Commentary/Commentary. Mikesh, Leann: Crow, Shelia: Bulluck, Grant.Alaedini, Armin; Green, Peter H R.(Feb 15, 2005). Narrative Review: Celiac Disease: Understanding a Complex Autoimmune Disorder. Annals of Internal Medicine 142.4 pg. 289-98.Papp, Maria; Foldi,Ildiko;Nemes,Eva;Udvary, Miklo; Harsfalvi,Jolan (Apr 2008). Haptoglobin Polymorphism: A Novel Genetic Risk Factor For Celiac Disease Developmental and Its Clinical Manifestions. Clinical Chemistry 54.4, pg. 697704.Gelfond, Daniel; Fasano, Alessio.(Apr 2006) Celiac Disease in the Pediatric Population, Pediatric Annals 35.4, pg. 275-9.Brar, Pardeep;Lee, Ann R; Lewis, Suzanne K; Bhagat, Govind;Green Peter H R.(May 2006) Celiac Disease in African Americans, Digestive Diseases and Sciences 51.5, pg. 1012-5.Pynnonen, Paivi A; Isometsa, Erkki T; Aronen, Eeva T; Verkasalo, Matti A;( Jul/Aug 2004), Mental Disorders in Adolescents With Celiac Disease, Psychosomatics 45.4, pg. 325-35.Ciacci, C; D'Agate, C; De Rosa, A; Franzese, C; (Nov 2003), SelfRated Quality of LIfe in Celiac Disease, Digestive Disease and Sciences 48.11, pg. 2216-20.Ciacci, Carolina; Iavarone, Alessandro; Siniscalchi, Monica; Romano, Rita; De Rosa, Antonio; ( Sept 202) Psychological dimensions of celiac disease: Toward a intergrated approach; Digestive Diseases and Sciences 47.9, pg. 20827.Schneider, Mary-Jane (2011) Introduction to Public Health, Sudbury, MA, Jones and Bartlett Publishers, p233, 4.http://en.wikipedia.org/wiki/Transtheoretical_modelhttp://www.celiaccentral.org/PrivacyPolicy/27/http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm265212.htm • Music by Johnny Cash, I’ve been everywhere recorded in 1996 . Free Powerpoint Templates Page 29