Transcript Oral Presentation #1

A Novel Dermoscopic Probe for Determining
Elasticity Measurements of the Skin
Group 7:
Erica Bozeman
Markesha Cook
Stephanie Cruz
November 14, 2006
Design Objective

"Structural alterations within cancerous skin-lesions cause
unexpected patterns of anatomical deformation in response to
mechanical forces."
Dr. Michael Miga

create a novel dermoscopic imaging probe

conduct phantom experiments

design skin-friendly stretching apparatus
Skin Cancer

Types of skin cancer
 Basal Cell carcinoma
 Squamous cell carcinoma
 Melanoma

Risk Factors
 Chronic overexposure to sun
 Skin type
 Number of moles
 History
 Weakened immune system

Areas Frequently Affected
 Face, neck, hand, shoulders, back,
arms
http://images.main.uab.edu/healthsys/ep_0137.jpg
Current Methods of Detection

Physician

Visual Inspection

Biopsy
 Invasive
 Scarring
 Time
 Misdiagnosis

Dermoscopy
http://www.jfponline.com/images/5206/5206JFP_AppliedEvidence-fig4.jpg
Our Proposed Device

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Easy
Non-invasive
Quick
Effective
Cost-efficient
Design Specifications:
Probe Design

Metal/plastic shaft

Apply controlled tensile stretch
A
few mm
 Adhesive applied to skin
 Crank ~ Crescent wrench

Hold camera
Potential Design:
Force
Sensor
Mild Skin
adhesive
Sony XCDX710CR camera
Testing Methods

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Uniaxial Tension
Simple Finite Element
Method
Viscoelastic parameters
of the skin
Independent Testing
with the Bose
ElectroForce ©
Elastography
http://www.boseelectroforce.com/product.cfm?pid=41&sid=1
Budget

Force Sensor


Probe Materials


$128.00-$195.00
$100.00
3M Micropore Surgical tape

$10.00
Design Specifications:
Thin Film Load Cell

Strain Gauge Technology




Mechanical motion  electronic
signal
Measures force/displacement
Placed near stretching valve
Cost:$195
Future Work

Select force sensor


Research linear force actuatorsvalve


Measure ~2-5 Newtons
Provide electric constant force
Shaft material

Acrylic vs. Metal
http://www.beikimco.com/products/linearvoicecoil.php
Timeline
Important Design Dates

End of January


Mid February


Incorporate force sensors into probe design
Mid March


Fully functional probe
Comparative analysis using Dr. Miga’s model
April

Finalize results; prepare for design presentation
References

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www.skincancer.org
http://www.eurekalert.org/pub_releases/2006-10/osoa-ltt101606.php
http://www.smdsensors.com/detail_pgs/s100.htm
http://www.omega.com/literature/transactions/volume3/strain.html
M. I. Miga, M. P. Rothney, J. J. Ou, "Modality independent
elastography (MIE): Potential applications in dermoscopy", Medical
Physics, vol. 32, no. 5, pp. 1308-1320, 2005.
Tsap, Leonid V. et al. Efficient Nonlinear Finite Element Modeling
of Nonrigid Objects via Optimization of Mesh Models. Computer
Vision and Image Understanding. Vol 69, No. 3 March 1998 pp. 330350.
Wan Abas, W.A.B and J.C. Barbenal. Uniaxial Tension Test of
Human Skin In Vivo. J. Biomed. Engng. Vol 4 January 1982 pp.6571.
Questions