Transcript White Sponge Nevus

White Sponge Nevus
aka: Cannon's disease or familial white folded mucosal dysplasia
Brittney Short
Date: 11/09/2010
Name of Syndrome:
Patient:
Silas Carter
Age:
24
Gender:
male
Height:
6’0”
Weight:
175
Vital Signs:
HR: 70 bmp
Respiratory rate: 15 bpm
Blood Pressure: 125/86
Temperature: 98.5 °F
Chief
complaint
The color and appearance is not pleasant, but
there is no pain.
Medical
Alert
none
White Sponge Nevus
Cause of Syndrome - Medical History (if
applicable)
White Sponge Nevus is an autosomal-dominant
inheritance. The cause is a mutation in the mucosal
keratin 4 or keratin 13 genes. Since it is inherited, it can
be present at birth or at puberty.
It is a benign, uncommon, and predominantly affects
non-keratinized stratified-squamous epithelia
Age/race/sex predilections and Systemic Clinical
Features:
White Sponge Nevus can effect men OR women
of every race. If a parent has the disease, their
child has a 50:50 chance of getting inheriting
White Sponge Nevus.
Orofacial Clinical Features
It presents in the mouth, most frequently as a
thick bilateral white plaque with a spongy
texture, usually on the buccal mucosa, but
sometimes on the labial mucosa, alveolar ridge
or floor of the mouth. The gingival margin and
dorsum of the tongue are almost never affected.
Although this condition is perfectly benign, it is
often mistaken for leukoplakia
Radiographic Features of this
Syndrome
none
Special considerations in Treatment of this patient? How is it Diagnosed?
How common is it? Is it a horse or zebra?
- White Sponge Nevus is very uncommon.
-It is definitely a zebra, and it is often misdiagnosed. It is often thought to be thrush (oral
candidiasis), cheek biting, lichen planus, lupus erythematosus, hereditary benign intraepithelial
dyskeratosis, tobacco-induced keratotic lesions, pachyonychia congenita, and keratosis follicularis.
-It is diagnosed by a biopsy of the lesion(s).
-The histopathology of white sponge naevus is very characteristic and in particular shows
extensive areas of large clear skin cells in the epidermis.
There is no treatment for White Sponge Nevus. Usually, when doctors first see the characteristics,
they try an anti-fungal, but this condition will not respond to such treatment.
At times, the rare case of a plaque which extends onto the lip vermilion and is surgically removed
for aesthetic reasons.
Pictures of Disease or Syndrome
Intraoral Pictures
List Sources and References (This should be more than your text book!)
"White Sponge Nevus." Dermatology Online Journal. Web. 03 Nov. 2010.
<http://dermatology.cdlib.org/145/nyu/cases/112106_3.html>.
"White Sponge Nevus." Dermatology Online Journal. Web. 03 Nov. 2010.
<http://dermatology.cdlib.org/145/nyu/cases/112106_3.html>.
Ibsen, Olga A. C., and Joan Andersen. Phelan. Oral Pathology for the Dental
Hygienist. St. Louis, MO: Saunders/Elsevier, 2009. Print.