Transcript Chapter 12_Active_Lecture_Questions

Active Lecture Questions for
BIOLOGY, Eighth Edition
Neil Campbell & Jane Reece
Chapter 12
The Cell Cycle
Questions prepared by
Louise Paquin,
McDaniel College
Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.
Prokaryotic Division
Why don’t prokaryotic cells need to go through the
same cell cycle as eukaryotic cells?
Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.
S Phase
How might you prove experimentally that DNA
replication (and therefore the replication of
chromosomes) happens during the S phase of the
cell cycle and not during mitosis?
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Chromosomes in the Cell Cycle
At what part of the cell cycle
would you see a chromosome
that looks like this?
Give your reasons.
Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.
Evolution
What do the differences
among the division of these
cells demonstrate?
Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.
Kinetochore
Which of the following best describes the kinetochore?
a) a structure composed of several proteins that associate with
the centromere region of a chromosome and that can bind to
spindle microtubules
b) the centromere region of a metaphase chromosome at which
the DNA can bind with spindle proteins
c) the array of vesicles that will form between 2 dividing nuclei
and give rise to the metaphase plate
d) the ring of actin microfilaments that will cause the appearance
of the cleavage furrow
e) the core of proteins that forms the cell plate in a dividing plant
cell
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Rate of Mitosis
If you were to examine a sample of connective
tissue cells from a small but adult mammal and a
second sample from a fetus of the same species, in
which would you expect to find more cells
undergoing mitosis?
Why?
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Regulation of the Cell Cycle
A. What would you expect to happen if you fuse
a cell in S with a cell in G1?
Why?
B. What would you expect to happen to a nucleus
from a G1 cell if it is introduced into an
enucleated M cell?
Why?
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Regulation
Which of the following would need to be present to
produce a realistic signal to control the cell cycle?
(More than one may be required.)
a) a set of molecules that are sensitive to fluctuations
in the abundance of regulators
b) protein kinases
c) molecules that activate kinases
d) molecules that degrade activators
e) ability of the regulators to respond to signals from
outside the cell
f) signals from cellular surveillance
Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.
Cancer Cells
At which part of the cell cycle would you expect
that a change in regulation could result in cancer?
Provide a reason for your answer.
Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings.