Transcript Mitosis - Siegel High School

&
SPI.1.6 Determine the relationship
between cell growth and cell
reproduction.
Multicellular
• Growth
• Repair
Unicellular
• Reproduction
–Binary fission
http://www.biology.arizona.edu/cell_bio/tutorials/cell_cycle/cells2.html
MITOSIS
G2
(Gap 2)
1
M
2
G1
(Gap 1)
S-Phase
(DNA SelfReplication)
THE
CELL
CYCLE ~
The Life
Cycle of
The Cell
• Purpose: Form TWO Nuclei
• Goal:
–Same kind of DNA
–Same number of DNA
Chromosome
Condensed
(wrapped up)
Chromatin
Thin thread like
Chromatid
2 chromosomes held
together by a
centromere
INTERPHASE:
Gap 1
Normal cell
functions
INTERPHASE is
not a stage of
mitosis !
Gap 2
Prep for
Mitosis
Biological Science, a Molecular Approach.
BSCS Blue Version. Heath and Company, 1996.
S-phase
Synthesis of
DNA
Nuclear
membrane
present
Centrioles
Nucleolus
visible
DNAchromatin
Centrioles
migrate to poles
of the cell
Spindle
forms
nuclear
envelope
disappears
nucleolus
disappears
chromosomes
condense
____________
This organizes
the DNA
Chromatids
line
up in the
MIDDLE
of the cell
Middle of the
cell is called
the equator..
__________
Chromatids move
AWAY…
Chromatids separate
& move towards
the poles
Chromosome unwind
into chromatin
Spindle fibers
disappear
Nuclear
membrane
reforms
Nucleolus
reappears
1
5
2
3
4
6
7
• The division of the cytoplasm and the rest of the cell besides the
nucleus.
Plant
• Cell Plate
• Inside  Out
Animal
• Cleavage Furrow
• Outside  In
•
•
•
•
Uncontrolled cell growth
Cells do not respond to regulation signals
Cause tumors
Defect in tumor
suppressor gene