Transcript Case Investigations in Human Biology and Global Health

Case Investigations in
Human Biology and
Global Health
Marion Field Fass
Ethel D. Stanley
Julie A. Seiter
Margaret A. Waterman
Pedagogy
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Cyberlearning
• Data sets
• Mapping
• Graphing
• Videos
• Models/simulations
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Civic Engagement
Integrative Thinking
Introduction
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Health and
human
rightsClean water,
good food
and an
educated
mother
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public health;
agent host
and
environment,
thinking at
the
population
level
Mothers and babies
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Challenge of human
birth: maternal
mortality, infant
mortality,
complications of
birthing
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Graphing, modeling
Women’s rights play in
the access to care
Child health is related
to a healthy mom,
clean water, safe food,
feeding practices.
Food
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Double burden of
malnutrition,
undernutrition and
obesity
Vitamins and
minerals, proteins,
fats
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The Associated Press
Fri., June 19, 2009
impact of child
nutritional status,
dietary choices
constrained by
poverty, mapping,
visual learning-
Mosquito diseases
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Blood and its
functions, anemia,
parasitic disease vs
viral disease
Oxygen is the terminal
electron acceptor
concept of vector
Humans in environment,
genetic changes in vector,
pathogen that enable
pathogen to reach new
“virgin” audiencesEpidemiology, impact of
climate change
HIV
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HIV,
immune system,
Biological challenge of
Prevention,
biology of treatment
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Identifying factors
that create conditions
for spread- with HIV
these are strikingly
socialEpidemiology, global
and US,
new strategies for
prevention
Tuberculosis
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TB,
lung anatomy and
phys,
concepts of infectious
disease,
drugs and drug action,
begin resistance
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Interaction of
environment,
evolution of pathogen,
problems of noncompliance with
drugs,
DOTS (directly
observed therapy),
need for new tests
MRSA and the Rise of Antibiotic
Resistance
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MRSA
Bacterial mutation,
conjugation
Food supply,
Hospitals
Humans in larger
environments
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Spread of MRSA from
hospital to environment
now to food sourcesInteraction of
environment,
evolution of pathogen,
problems of noncompliance with drugs,
antibiotic misuse
Disease control and eradication
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Immunizationsmeasles, mumps,
rubella, but what
about HPV?
What is global picture?
Disease erad- must
do smallpox, maybe
polio- maybe
eradicatable
pathogens-
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The public health part
is strategies for
disease controlvaccination vs
treatment;
environmental
strategies,
reduction of pool of
susceptibles (herd
immunity) and
then loss of fear in
populations
Influenza
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Mutating virusits not just the
developing world
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Epi,
history,
mechanisms
of control of
diseases in
populations,
mapping and
surveillance
Heart disease
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Heart physiology,
back to genetics,
treatments,
scope of the problem
Oxygen is the terminal
electron acceptor
Major causes of death
in developed world
How / when do
developing countries
catch up?
Diabetes
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Endocrine system
Mechanisms of insulin
action, resistance to
insulin
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Lots of epidemiology,
changes in food and
diabetes,
long term impact of
diseases and
burden of Years of
Productive Live Lost
(YPLL) and DALYs
(Disability Associated
Life Years)
Tobacco
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CANCER (all cancer is
genetic although not all
cancer is inherited),
heart disease,
Lung diseases (COPD)
Interaction of smoking and
environment and second
hand smoke
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just when we thought
everything was OK the
industry guys promoted
tobacco use
Long term impacts of
health habits,
life table analysis,
comparisons globally,
role of WHO in this work,
industry vs advocates.
WHO Convention on
Tobacco, international
collaboration.
bill gates and michael
bloomberg think its
important
Beijing Blue
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Human biology, global
health and
environmental
changethe impact of the
environment on
human physiology and
health
Measuring on
particulates
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it follows from host –
agent- environment
Population thinking
International efforts to
mitigate air pollution