Transcript Robert_Koch[1]final[1].

Robert Koch
Father of Bacteriology
Tom Souza
Tobey Stohr
Thank You
Definitions
• Anthrax- Spread from animals to humans thru
contaminated wool, from eating uncooked meat or
breathing in airborne spores
• Cholera- An infection of the small intestines which
causes watery diarrhea. Severe dehydration is a result
• Tuberculosis- Spread from person to person thru
the air, in tiny microscopic droplets. A person with TB
coughs or sneezes, the bacteria can be inhaled by
persons nearby
Postulates for Indentifying
• Discovered a set of guidelines for culturing bacteria
• In 1890, presented what is now called Koch's
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postulates, four rules still used for determining whether
a given bacteria is the cause of a specific disease
1. The bacteria must be present in every case of the
disease.
2. The bacteria must be isolated from the host with the
disease and grown in pure culture.
3. The specific disease must be reproduced when a pure
culture of the bacteria is inoculated into a healthy
susceptible host.
4. The bacteria must be recoverable from the
experimentally infected host.
Early Life
• Born Dec 11, 1843 in Clausthal, Germany
• Father’s a miner
• Showed signs of significant intelligence at
young age
• Showed interest in Biology throughout
high school
• Had a strong urge to travel
Early Life continued…
• In 1862, he went to the University of
Gottingen
• Worked as a volunteer medical officer
during the Franco-Prussian War
• Worked in a hospital for general practice
with microbiology
Anthrax
• Sought out causes for the anthrax bacillus
• Inoculated mice with wood splinters
• Once he checked the spleen of infected
farm animals, he found out that the
disease had killed them, and healthy mice
in which he inoculated with the blood of
other healthy farm animals had no
infection
Anthrax continued…
• Koch wanted to find out primary source of
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anthrax
Made culture on the surface of an ox’s eye
Found another discovery of the anthrax
Spores would cause the bacteria to be able to
grow again once conditions were live sustaining
again.
Theory showed that anthrax could survive in
without a host for an extended period of time
Koch gets Famous
• Continued work at the University of
Breslau
• My colleagues published a journal of
Koch’s work and quickly became famous
• Worked for four years improving theories
Work on Tuberculosis
• 1st presented discovery of TB to an audience in
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1882
Made the conclusion that 1 in 7 humans at that
time would die from TB
Described how I had invented a new straining
method and demonstrated for the audience
Showed the audience of the devastating disease
and how it was contracted
Work was published on April 10, 1882
Tuberculosis Continued…
• Continued work on Tuberculosis as the
Head Director of the Institute of Infectious
Diseases
Cholera
• Koch went to Alexandria, Egypt in 1883 to
do research on Vibrio Cholerae
• Was pronounced the leading role in the
German Cholera Commission
• He did his research on what the virus was
and was able to identify it was Cholera
• He attempted to infect animals with
cholera, but none became infected
Cholera continued…
• Koch and his team travelled to Calcutta, India to further study the
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disease
In India, Koch was able to find a pure Culture of Cholera
Made the conclusion that cholera is not susceptible to animals
Proved the miasma theory false
His work proved that cholera was a human borne disease
He returned to Berlin in 1884 with all of his findings on Cholera
His work allowed him to formulate proper decisions on how to
control the Cholera outbreak
Some of these ideas are still used today
Koch received a gift of 100,000 German Marks for his discovery
His ideas also helped formulate decisions on the conservation of
water supplies
Other Significant Achievements
• Koch was appointed the Professor of Hygiene at
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the University of Berlin
He was appointed the Surgeon General in 1890
In 1891, he became the professor of the new
medical faculty and the director of the Institute
of Infectious Diseases
Followed work in India and Africa on malaria,
black water fever, surra of cattle and horses and
plague
Nobel Prize
• Koch was awarded the Nobel Prize in
Medicine
• Received a diploma directly from the
hands of the King of Sweden
• Was awarded 10 million SEK
Robert Koch Award
• Robert Koch passed away May 27, 1910 of
heart failure in Baden-Baden, Germany
• Since 1970, there have been a handful of
biomedical scientists which have received
the award for their work for finding new
cures etc.