The human fecal transplant
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Transcript The human fecal transplant
THE HUMAN FECAL
TRANSPLANT
- Laura Ann McCann
Clostridium difficile
Also known as C. diff
Mild to moderate symptoms: watery diarrhea, abdominal pain and
cramping
Severe symptoms: colitis, watery diarrhea from 10-15 times per
day, fever, nausea
Transmission: fecal-oral and while taking certain antibiotics
Produces spores that can survive in a room for weeks to months
Treatment: Flagyl or vancomycin and surgery for severe cases
Causes approximately 14,000 deaths annually
HUMAN FECAL TRANSPLANT
Donated stool from a healthy person is transplanted into a patient
infected with the C. diff bacterium
The patient that receives the stool has not been responding to the
traditional antibiotics
Administration: nasogastric tube or implantation during a colonoscopy
Most symptoms are relieved within 24 hours
The donated stool helps regenerate and re-establish the regular
intestinal flora in the patient’s gastrointestinal tract
STUDY PRESENTED AT THE ANNUAL INFECTIOUS
DISEASE SOCIETY OF AMERICA MEETING IN SAN DIEGO
49 patients that were not responding to antibiotics were treated
43 recovered completely and did not have any side effects or
recurrence 3 months later
4 died from causes not related to C. diff or treatment
One showed no improvement
http://www.medicalnewstoday.com/articles/251759.php
http://news.yahoo.com/poop-transplants-may-combat-bacterialinfections-130609662.html